Bis(4-fluorophenyl)phenylphosphine oxide
Bis(4-fluorophenyl)phenylphosphine oxide (CAS 54300-32-2) is an organophosphorus compound with the linear formula (FC6H4)2P(O)C6H5, molecular formula C18H13F2OP and a molar mass of 314.27 g/mol. Supplied as a crystalline solid melting at about 125-131 degC, it is a fluorinated tertiary phosphine oxide used in catalysis and in chemical synthesis, notably as a building block for fluorinated and chlorine-tolerant polymers and as a hydroformylation catalyst component.
- Synonyms
- Bis(4-fluorophenyl)phenylphosphine oxideBis(p-fluorophenyl)phenylphosphine oxideDi(4-fluorophenyl)phenylphosphine oxidePhenylbis(4-fluorophenyl)phosphine oxide(4-FC6H4)2P(O)PhCAS 54300-32-2

Hydroformylation catalysis
Acts as a phosphine-derived catalyst component in hydroformylation (oxo) reactions, where the phosphorus centre helps modulate the activity and selectivity of transition-metal systems.
Chlorine-tolerant desalination polymers
Serves as a monomer or building block in the preparation of chlorine-tolerant polymers developed for reverse-osmosis and desalination membranes, exploiting the stability conferred by its aromatic C-F bonds.
Fuel-cell membrane crosslinking
Used as a crosslinking agent in the preparation of polymer electrolyte membranes for fuel-cell applications, contributing to the mechanical and chemical robustness of the membrane network.
Fluorinated organophosphorus synthesis
Functions as an intermediate and reference reagent in research-scale synthesis of fluorinated phosphine and phosphine-oxide derivatives, where the para-fluoro substituents provide defined reactivity and a 31P/19F NMR handle.
| Molecular weight | 314.27 |
|---|---|
| Linear formula | (FC6H4)2P(O)C6H5 |
| Assay | 97% |
| Application | • Catalyst for hydroformylation reactions1• Used for preparation of chlorine-tolerant polymers for desalination2• Crosslinking agent in preparation of polymer electrolyte membranes for fuel cell applications3 |
| Melting point | 125-131 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(4-fluorophenyl)phenylphosphine oxide used for?
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It is used mainly in catalysis and polymer chemistry. Documented uses include serving as a catalyst component for hydroformylation reactions, as a building block for chlorine-tolerant polymers for desalination, and as a crosslinking agent in polymer electrolyte membranes for fuel cells. It also serves as a reagent for the synthesis of fluorinated organophosphorus compounds.
What is the CAS number and molecular formula of Bis(4-fluorophenyl)phenylphosphine oxide?
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Its CAS number is 54300-32-2 and its molecular formula is C18H13F2OP, written as the linear formula (FC6H4)2P(O)C6H5. The molecular weight is 314.27 g/mol, with EC number 259-079-7 and MDL number MFCD00239478.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(4-fluorophenyl)phenylphosphine oxide at a typical assay of 97% as a research and technical-grade reagent for synthesis and laboratory use. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements for this compound?
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It is classified under GHS07 with the signal word Warning and the hazard statements H302, H312, H315, H319, H332 and H335: it is harmful if swallowed, in contact with skin or if inhaled, and causes skin and serious eye irritation and may cause respiratory irritation. Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and follow the precautionary measures P261, P280 and P305+P351+P338. It carries Water Hazard Class WGK 3 (Germany), so releases to water must be prevented. Always consult the SDS before use.
How is Bis(4-fluorophenyl)phenylphosphine oxide packed, shipped and exported?
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It is supplied as a solid in tightly sealed containers sized to the order, from gram-scale laboratory quantities to larger research and bulk requirements, with full labelling and documentation. As a global supplier and exporter, Tech Serve Solutions handles export packing and shipping with a certificate of analysis and an SDS, and prepares the relevant transport and customs paperwork for your destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name, CAS number 54300-32-2, the grade or assay you need and your required quantity. We will respond with availability, lead time, packing options and a formal quotation, and can arrange a sample where appropriate.
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