Bis(3,5-dimethylphenyl)phosphine
Bis(3,5-dimethylphenyl)phosphine (CAS 71360-06-0; C16H19P; molar mass 242.30 g/mol) is an air-sensitive secondary organophosphine bearing a reactive P-H bond and two 3,5-xylyl (3,5-dimethylphenyl) substituents. Supplied as a clear liquid (density 1.017 g/mL at 25 C, refractive index n20/D 1.599), it serves chiefly as a building block and ligand precursor in organophosphorus synthesis and transition-metal catalysis. Tech Serve Solutions supplies it to research, fine-chemical and laboratory users worldwide.
- Synonyms
- Bis(3,5-dimethylphenyl)phosphineDi(3,5-xylyl)phosphineBis(3,5-xylyl)phosphineC16H19P

Phosphine ligand precursor
The reactive P-H functionality allows elaboration into tertiary phosphines and phosphine ligands used to support transition-metal catalysts. The two 3,5-dimethylphenyl groups provide defined steric and electronic character around phosphorus.
Organophosphorus synthesis
Used as a versatile building block for constructing phosphorus-containing molecules, including via P-H addition, metalation and substitution chemistry common to secondary phosphines.
Homogeneous catalysis research
Phosphine compounds of this type are studied as components of metal complexes for catalytic transformations. Specific catalyst systems should be developed and validated by the user for their intended reaction.
Laboratory reagent and intermediate
Functions as a research-grade intermediate and phosphorus precursor for method development and small-scale synthesis in academic and industrial laboratories.
| Molecular weight | 242.30 |
|---|---|
| Empirical formula | C16H19P |
| Density | 1.017 g/mL at 25 °C |
| Refractive index | n20/D 1.599 |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(3,5-dimethylphenyl)phosphine used for?
+
It is used mainly as a secondary phosphine building block and ligand precursor in organophosphorus synthesis and transition-metal catalysis research. Its reactive P-H bond allows conversion into tertiary phosphines and related phosphorus-containing compounds.
What is the CAS number and molecular formula of Bis(3,5-dimethylphenyl)phosphine?
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The CAS number is 71360-06-0 and the empirical formula is C16H19P (Hill notation), corresponding to a molecular weight of 242.30 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply Bis(3,5-dimethylphenyl)phosphine as a research/technical-grade reagent for synthesis and laboratory use; it is not represented as USP, BP or EP pharmacopoeia grade. A current specification and lot-specific data can be provided with your enquiry.
What are the safety and handling precautions?
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It is classified GHS07 with the signal word Warning and hazard statement H302 (harmful if swallowed). As an air-sensitive secondary phosphine, handle under inert atmosphere with eye and face protection, gloves and suitable respiratory protection, in a well-ventilated area, and consult the SDS before use.
How is Bis(3,5-dimethylphenyl)phosphine packed, shipped and exported?
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It is packed in appropriate sealed containers for an air-sensitive liquid and labelled to applicable standards. For transport it is assigned UN 3334; we arrange compliant documentation and export to laboratories and manufacturers worldwide. Packaging options can be tailored to your order.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity and destination, and we will confirm availability, specification, lead time and a quotation. Sample requests can be discussed at the same time.
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