Bis(1,5-cyclooctadiene)nickel(0)
Bis(1,5-cyclooctadiene)nickel(0), CAS 1295-35-8, is an organonickel(0) complex with the empirical formula C16H24Ni and a molecular weight of 275.06. Commonly abbreviated Ni(COD)2, it is a yellow, air- and moisture-sensitive crystalline solid widely used as a soluble source of zero-valent nickel in homogeneous catalysis. Tech Serve Solutions supplies it as a research-grade reagent for cross-coupling, cycloaddition and the in situ generation of nickel catalysts in synthetic and organometallic chemistry.
- IUPAC
- Bis(cyclooctadiene)nickel,Ni(COD)2
- Synonyms
- Bis(1,5-cyclooctadiene)nickel(0)Bis(cyclooctadiene)nickelBis(1,5-cyclooctadiene)nickelNi(COD)2Nickel(0) bis(1,5-cyclooctadiene)1,5-Cyclooctadiene nickel(0)CAS 1295-35-8
Source of zero-valent nickel
Ni(COD)2 serves as a convenient, soluble precursor of Ni(0) in organometallic chemistry. Its labile 1,5-cyclooctadiene ligands are readily displaced by phosphines, N-heterocyclic carbenes and other donors to generate active nickel catalysts in situ.
Cycloaddition of 1,3-dienes
The complex acts as a catalyst for the cycloaddition of 1,3-dienes, supporting the construction of carbocyclic frameworks in synthetic organic chemistry.
Nickel-catalysed cross-coupling
As a precatalyst, Ni(COD)2 is widely employed in non-precious-metal cross-coupling and C–C and C–heteroatom bond-forming reactions, offering an economical alternative to palladium in many transformations.
Organometallic and catalysis research
It is a standard reagent for the preparation of defined nickel complexes and for mechanistic and methodology studies in homogeneous catalysis and coordination chemistry.
| Molecular weight | 275.06 |
|---|---|
| Empirical formula | C16H24Ni |
| Storage temperature | −20°C |
| Application | Catalyst for the cycloaddition of 1,3-dienes.8 |
| Melting point | 60 °C (dec.)(lit.) |
Hazard statements
- H228Flammable solid
- H334May cause allergy or asthma symptoms if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P342
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-40 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(1,5-cyclooctadiene)nickel(0) used for?
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It is used principally as a soluble source of zero-valent nickel in homogeneous catalysis. The two 1,5-cyclooctadiene ligands are easily replaced by other donors to form active nickel catalysts in situ, and the complex itself catalyses the cycloaddition of 1,3-dienes and supports nickel-catalysed cross-coupling reactions.
What is the CAS number and molecular formula of Bis(1,5-cyclooctadiene)nickel(0)?
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The CAS number is 1295-35-8. The empirical formula in Hill notation is C16H24Ni, with a molecular weight of 275.06. It is also identified by EC number 215-072-0, MDL number MFCD00058902 and PubChem Substance ID 24854723.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(1,5-cyclooctadiene)nickel(0) as a research/reagent-grade organometallic material for synthesis and catalysis. We do not represent it as a USP, BP or EP pharmacopoeial grade. Current assay, lot-specific specifications and a Certificate of Analysis are confirmed at the time of enquiry.
What are the safety and handling hazards of Ni(COD)2?
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It carries the GHS signal word Danger with pictograms GHS02 and GHS08. The hazard statements are H228 (flammable solid), H334 (may cause allergy or asthma symptoms or breathing difficulties if inhaled) and H351 (suspected of causing cancer). The material is air- and moisture-sensitive and should be handled under inert atmosphere using suitable eye, face and respiratory protection and gloves, and stored cold at around −20°C. It is classified WGK 3 (severe hazard to waters).
How is Bis(1,5-cyclooctadiene)nickel(0) packed, shipped and exported?
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As an air-sensitive flammable solid, it is packed under inert atmosphere in sealed containers and held cold. For transport it is classified UN 1325, Class 4.1 (flammable solid, organic), Packing Group II. Tech Serve Solutions arranges compliant, fully documented packaging and export shipping with appropriate dangerous-goods declarations and a Certificate of Analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, specification and destination, and our team will respond with availability, lead time, documentation and a formal quotation. Samples may be available subject to the dangerous-goods and quantity constraints of this material.
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