Fmoc-Tmb-Gly-OH
N-Fmoc-N-(2,4,6-trimethoxybenzyl)glycine (CAS: 166881-43-2) is a specialised amino acid derivative with the empirical formula C27H27NO7 and a molecular weight of 477.51 g/mol. This compound is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its structure facilitates controlled reactions in the development of complex biomolecules and research probes. TSS supplies this product at a minimum purity of 97.0% via HPLC.
- IUPAC
- N-Fmoc-N-(2,4,6-trimethoxybenzyl)glycine
Peptide Synthesis
This Fmoc-protected glycine derivative serves as a building block in solid-phase peptide synthesis. The N-Fmoc group allows for orthogonal deprotection strategies, enabling controlled chain elongation in complex peptide sequences.
Chemical Biology Research
It is employed in the construction of modified peptides or peptidomimetics for investigating biological pathways. The N-terminal protection and specific side-chain moiety offer unique properties for designing probes.
Organic Synthesis
Beyond peptides, this compound can be a valuable reagent in general organic synthesis where a protected glycine unit with specific steric or electronic properties is required.
| Molecular weight | 477.51 |
|---|---|
| Empirical formula | C27H27NO7 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Tmb-Gly-OH used for?
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Fmoc-Tmb-Gly-OH is used in chemical synthesis, particularly in peptide chemistry and chemical biology research, as a protected glycine building block for constructing complex molecules.
What are the CAS number and chemical formula for Fmoc-Tmb-Gly-OH?
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The CAS number is 166881-43-2, and the empirical formula is C27H27NO7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Fmoc-N-(2,4,6-trimethoxybenzyl)glycine with an assay of ≥97.0% determined by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for Fmoc-Tmb-Gly-OH?
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This compound is classified as Dangerous (GHS06) and carries hazard statements including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), and H413 (May cause long lasting harmful effects to aquatic life). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator, is essential during handling. Store at 2-8°C.
How is Fmoc-Tmb-Gly-OH packed and shipped?
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Fmoc-Tmb-Gly-OH is shipped as UN 2811, Class 6.1, Packing Group III. Packaging complies with international regulations for the transport of hazardous chemicals. Tech Serve Solutions is an experienced global exporter.
How can I request a sample or quote for Fmoc-Tmb-Gly-OH?
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To request a sample or a quotation, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
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