Fmoc-Thr-OH monohydrate
Fmoc-Thr-OH monohydrate (CAS: 73731-37-0), with the molecular formula C19H19NO5 · H2O and a molecular weight of 359.37, is a crucial derivative of the amino acid threonine. This compound is widely employed in peptide synthesis, serving as a protected building block for creating complex peptide chains. Its monohydrate form ensures stability and ease of handling in various chemical and biochemical research applications. Tech Serve Solutions provides this high-quality reagent for demanding synthetic pathways.
- IUPAC
- Fmoc-L-threonine monohydrate
Peptide Synthesis
Fmoc-Thr-OH monohydrate is a fundamental building block in solid-phase and solution-phase peptide synthesis. The Fmoc protecting group allows for sequential deprotection and coupling reactions, enabling the controlled assembly of peptide sequences.
Chemical Biology
This threonine derivative is utilised in chemical biology research for the synthesis of modified peptides and peptidomimetics. These can be used to probe biological processes or as components of novel therapeutic agents.
Organic Synthesis
Beyond peptide chemistry, Fmoc-Thr-OH monohydrate can serve as a chiral starting material or intermediate in various complex organic synthesis projects requiring the introduction of a threonine moiety.
| Molecular weight | 359.37 |
|---|---|
| Empirical formula | C19H19NO5 · H2O |
| Assay | ≥98.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −16±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Thr-OH monohydrate used for?
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Fmoc-Thr-OH monohydrate is primarily used as a protected amino acid building block in peptide synthesis and in chemical biology research for creating modified peptides and peptidomimetics.
What are the CAS number and formula for Fmoc-Thr-OH monohydrate?
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The CAS number is 73731-37-0, and the empirical formula is C19H19NO5 · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Thr-OH monohydrate with an assay of ≥98.0% (sum of enantiomers, HPLC). This is a research-grade chemical and is not represented as USP, EP, or BP grade.
How should Fmoc-Thr-OH monohydrate be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter may be necessary. Store at 2-8°C for optimal stability. The compound is classified under WGK Germany 3.
Is Fmoc-Thr-OH monohydrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-Thr-OH monohydrate.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team via the website or direct inquiry, providing the product name and CAS number.
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