Fmoc-Tic-OH
Fmoc-Tic-OH (CAS 136030-33-6), with the molecular formula C25H21NO4 and a molecular weight of 399.44 g/mol, is a key unnatural amino acid derivative. This compound is utilised in specialised chemical synthesis and peptide chemistry. Its primary application lies in the construction of complex peptide chains and in chemical biology research where modified amino acid residues are required for specific functionalities.
- IUPAC
- (S)-N-Fmoc-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Peptide Synthesis
Fmoc-Tic-OH serves as a building block in solid-phase peptide synthesis (SPPS) utilising the Fmoc protecting group strategy. It allows for the incorporation of the tetrahydroisoquinoline-3-carboxylic acid moiety into peptide sequences.
Chemical Biology Research
As an unnatural amino acid derivative, it is employed in designing peptides with altered structural or functional properties. This enables the study of protein-peptide interactions and the development of novel biomolecules.
Medicinal Chemistry
The unique structural features of Fmoc-Tic-OH can be exploited in medicinal chemistry programmes to develop novel drug candidates with specific pharmacological profiles.
| Molecular weight | 399.44 |
|---|---|
| Empirical formula | C25H21NO4 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/D +26.0±3.0°, c = 1% in methanol |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Tic-OH used for?
+
Fmoc-Tic-OH is primarily used in peptide synthesis and chemical biology research as an unnatural amino acid derivative for building specialised peptide chains and investigating biomolecular interactions.
What is the CAS number and formula for Fmoc-Tic-OH?
+
The CAS number for Fmoc-Tic-OH is 136030-33-6, and its empirical formula is C25H21NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fmoc-Tic-OH with an assay of ≥97.0% (HPLC). This is a research or technical grade material; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Tic-OH be handled safely?
+
Handle Fmoc-Tic-OH with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or P1 (EN143) respirator filter if airborne exposure is possible. Refer to the safety data sheet for full handling instructions.
How is Fmoc-Tic-OH shipped and exported?
+
Fmoc-Tic-OH is stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments.
How can I request a sample or quote for Fmoc-Tic-OH?
+
To request a sample or a quotation for Fmoc-Tic-OH, please contact the Tech Serve Solutions sales department via our website or direct contact details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis