Fmoc-Thr(PO3BzlH)-OH
Fmoc-Thr(PO3BzlH)-OH (CAS: 175291-56-2) is a phosphorylated derivative of threonine, featuring the Fmoc protecting group. With a molecular weight of 511.46 g/mol and the empirical formula C26H26NO8P, this compound is a valuable building block in peptide synthesis and chemical biology research. Its structure allows for the incorporation of a phosphorylated threonine residue into peptide chains, facilitating the study of protein phosphorylation and related signalling pathways.
- IUPAC
- Fmoc-O-(benzylphospho)-L-threonine
Peptide Synthesis
Fmoc-Thr(PO3BzlH)-OH is utilized as a key intermediate in solid-phase peptide synthesis (SPPS) to incorporate phosphorylated threonine residues. This enables the creation of phosphopeptides for studying enzyme activity and protein interactions.
Chemical Biology
This compound serves as a crucial reagent in chemical biology for investigating signalling cascades and post-translational modifications. It aids in the synthesis of peptides and proteins with defined phosphorylation patterns for biological studies.
Drug Discovery
Researchers employ Fmoc-Thr(PO3BzlH)-OH in the development of novel therapeutic agents. The controlled incorporation of phosphorylated amino acids can influence peptide-based drug efficacy and pharmacokinetic properties.
| Molecular weight | 511.46 |
|---|---|
| Empirical formula | C26H26NO8P |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Thr(PO3BzlH)-OH used for?
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Fmoc-Thr(PO3BzlH)-OH is primarily used in peptide synthesis and chemical biology for the incorporation of Fmoc-protected, benzyl-phosphorylated threonine residues into peptide chains. This is vital for studying protein phosphorylation and related biological processes.
What is the CAS number and formula for Fmoc-Thr(PO3BzlH)-OH?
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The CAS number is 175291-56-2, and the empirical formula is C26H26NO8P.
What grade and purity does Tech Serve Solutions supply for Fmoc-Thr(PO3BzlH)-OH?
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Tech Serve Solutions supplies Fmoc-Thr(PO3BzlH)-OH with an assay of ≥97.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-Thr(PO3BzlH)-OH be handled and stored?
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Handle Fmoc-Thr(PO3BzlH)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at 2-8°C. The compound is classified under WGK 2 in Germany, indicating a hazard to water.
How is Fmoc-Thr(PO3BzlH)-OH packed, shipped, and exported?
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Fmoc-Thr(PO3BzlH)-OH is carefully packed to ensure integrity during transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a sample or quote for Fmoc-Thr(PO3BzlH)-OH?
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To request a sample or a quote for Fmoc-Thr(PO3BzlH)-OH, please contact our sales department via the website or direct email, providing your contact details and the quantity required.
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