Fmoc-Thr(Bzl)-OH
Fmoc-Thr(Bzl)-OH (CAS 117872-75-0) is a protected amino acid derivative with the molecular formula C26H25NO5 and a molecular weight of 431.48. It serves as a crucial building block in peptide synthesis, particularly for incorporating the O-benzyl protected threonine residue. This compound is essential in research and development for creating complex peptides with specific functionalities and structural properties.
- IUPAC
- Fmoc-O-benzyl-L-threonine
Peptide Synthesis
Fmoc-Thr(Bzl)-OH is a protected L-threonine derivative used extensively in solid-phase and solution-phase peptide synthesis. The Fmoc protecting group allows for selective deprotection under mild basic conditions, while the benzyl group protects the hydroxyl function of threonine during peptide chain elongation.
Chemical Biology Research
This compound is utilised in the synthesis of peptides designed for studies in chemical biology, enabling the investigation of protein structure-function relationships and the development of novel biomolecules. Its protected nature facilitates precise control over the synthetic process.
Organic Synthesis Intermediate
Beyond peptide synthesis, Fmoc-Thr(Bzl)-OH can be employed as an intermediate in complex organic synthesis pathways, where its specific structural features and protecting groups are advantageous for constructing elaborate molecular architectures.
| Molecular weight | 431.48 |
|---|---|
| Empirical formula | C26H25NO5 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Thr(Bzl)-OH used for?
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Fmoc-Thr(Bzl)-OH is primarily used as a building block in peptide synthesis, especially for incorporating O-benzyl protected threonine residues into peptide chains. It is also valuable in chemical biology research and as an intermediate in organic synthesis.
What is the CAS number and molecular formula for Fmoc-Thr(Bzl)-OH?
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The CAS number for Fmoc-Thr(Bzl)-OH is 117872-75-0, and its molecular formula is C26H25NO5.
What grade and purity does Tech Serve Solutions supply for Fmoc-Thr(Bzl)-OH?
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Tech Serve Solutions supplies Fmoc-Thr(Bzl)-OH with an assay of ≥98.0% determined by TLC. This product is suitable for research and chemical synthesis purposes. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should Fmoc-Thr(Bzl)-OH be handled and stored?
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Fmoc-Thr(Bzl)-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound should be stored at 2-8°C to maintain its stability.
Is Fmoc-Thr(Bzl)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Thr(Bzl)-OH is a controlled substance. Its WGK Germany classification is 3.
How is Fmoc-Thr(Bzl)-OH packaged and exported?
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Tech Serve Solutions expertly packages and exports fine chemicals globally, adhering to all necessary regulations for safe and secure transportation of chemical reagents.
How can I request a quote or sample of Fmoc-Thr(Bzl)-OH?
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To request a quote or a sample of Fmoc-Thr(Bzl)-OH, please contact the Tech Serve Solutions sales department via our website or by phone.
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