Fmoc-Ser-OH
Fmoc-Ser-OH (CAS: 73724-45-5), a derivative of the amino acid serine, is presented with the molecular formula C18H17NO5 and a molecular weight of 327.33 g/mol. This compound plays a crucial role in peptide synthesis due to the Fmoc protecting group, enabling controlled chain elongation. It is widely employed in chemical biology and synthesis, serving as a fundamental building block for complex peptide structures and modified amino acid research.
- IUPAC
- Fmoc-L-serine
- Synonyms
- Fmoc-L-serine

Peptide Synthesis
Fmoc-Ser-OH is a key reagent in solid-phase and solution-phase peptide synthesis, where the Fmoc group facilitates orthogonal protection strategies. It allows for the controlled introduction of serine residues into peptide sequences.
Chemical Synthesis
Beyond peptides, this compound serves as a versatile chiral building block in organic synthesis. Its functional groups can be manipulated for the creation of complex molecules and novel chemical entities.
Chemical Biology Research
Researchers utilise Fmoc-Ser-OH to synthesise modified peptides for studying biological processes, protein function, and enzyme interactions. It enables the incorporation of serine with a protected amine terminus into biomolecules.
| Molecular weight | 327.33 |
|---|---|
| Empirical formula | C18H17NO5 |
| Assay | ≥97.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −12.5±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Ser-OH used for?
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Fmoc-Ser-OH is primarily used as a protected amino acid building block in peptide synthesis and as a chiral intermediate in chemical synthesis and chemical biology research.
What are the CAS number and formula for Fmoc-Ser-OH?
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The CAS number for Fmoc-Ser-OH is 73724-45-5, and its empirical formula is C18H17NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Ser-OH with an assay of ≥97.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Ser-OH be handled and stored?
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Handle Fmoc-Ser-OH with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C. In Germany, it is classified under WGK 3, indicating a high hazard to water.
Is Fmoc-Ser-OH a controlled substance?
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The provided data does not indicate that Fmoc-Ser-OH is a controlled substance.
How can I request a quote or sample for Fmoc-Ser-OH?
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To request a quote or sample of Fmoc-Ser-OH, please contact our sales team through the website or by calling our office.
How is Fmoc-Ser-OH packed, shipped, and exported?
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Fmoc-Ser-OH is carefully packed to maintain its integrity during transit. As a global supplier, Tech Serve Solutions handles all necessary procedures for exporting chemicals worldwide.
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