Fmoc-Ser(PO3BzlH)-OH

CAS 158171-14-3C25H24NO8PChemical Synthesis

Fmoc-Ser(PO3BzlH)-OH (CAS: 158171-14-3) is a phosphorylated serine derivative used in peptide synthesis. With the molecular formula C25H24NO8P and a molecular weight of 497.43 g/mol, this compound is a valuable building block in chemical biology and synthesis. It facilitates the incorporation of phosphoserine residues into peptides, enabling the study of phosphorylation-dependent biological processes. TSS supplies this reagent for research and development purposes.

IUPAC: Fmoc-O-(benzylphospho)-L-serine

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Fmoc-Ser(PO3BzlH)-OH (C25H24NO8P) — chemical structure, CAS 158171-14-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistrySerine

01 /Applications

Peptide Synthesis

Fmoc-Ser(PO3BzlH)-OH serves as a protected phosphoserine building block for solid-phase peptide synthesis (SPPS). Its Fmoc group allows for orthogonal deprotection strategies, compatible with standard SPPS protocols.

Chemical Biology Research

This compound is instrumental in synthesising peptides that mimic post-translationally modified proteins. It aids in the study of protein function, signalling pathways, and enzyme activity regulation.

Development of Phosphopeptide Analogues

It enables the creation of stable phosphopeptide analogues for use in biochemical assays and drug discovery programmes. The benzyl protecting group on the phosphate offers specific cleavage conditions.

02 /Properties

Molecular weight	497.43
Empirical formula	C25H24NO8P
Assay	≥97.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

158171-14-3

MDL number

MFCD00797869

Beilstein registry

7060483

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Ser(PO3BzlH)-OH used for?

Fmoc-Ser(PO3BzlH)-OH is primarily used as a protected building block in the synthesis of phosphopeptides for research in peptide chemistry and chemical biology.

What are the CAS number and molecular formula of this compound?

The CAS number is 158171-14-3, and the molecular formula is C25H24NO8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Ser(PO3BzlH)-OH with an assay of ≥97.0% (HPLC). This product is intended for research and development and is not represented as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling considerations for Fmoc-Ser(PO3BzlH)-OH?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany, indicating a potential hazard to water.

How is Fmoc-Ser(PO3BzlH)-OH shipped and exported?

This chemical is typically stored at 2-8°C. Tech Serve Solutions is a global supplier and exporter, capable of handling international shipments of laboratory reagents and fine chemicals.