Fmoc-Ser(Trt)-OH

CAS 111061-56-4C37H31NO5Chemical Synthesis

Fmoc-Ser(Trt)-OH (CAS: 111061-56-4) is a protected amino acid derivative with the molecular formula C37H31NO5 and a molecular weight of 569.65 g/mol. This compound features an Fmoc protecting group on the alpha-amino nitrogen and a trityl group on the hydroxyl side chain of serine. It is primarily utilised in solid-phase peptide synthesis and other organic chemistry applications requiring controlled amino acid coupling.

IUPAC: Fmoc-O-trityl-L-serine
Synonyms: Fmoc-O-trityl-L-serine

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Fmoc-Ser(Trt)-OH (C37H31NO5) — chemical structure, CAS 111061-56-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAnalytical StandardsAnalytical/ChromatographyChemical BiologyChemical SynthesisFM - FZPeptide ChemistrySerine More...

01 /Applications

Solid-Phase Peptide Synthesis (SPPS)

Fmoc-Ser(Trt)-OH is a crucial building block in SPPS, enabling the stepwise assembly of peptide chains. The trityl protecting group offers robust protection for the serine hydroxyl functionality during coupling reactions.

Organic Synthesis

Beyond peptide synthesis, this compound serves as a chiral synthon in various organic transformations where a protected serine residue is required. Its specific functional groups allow for selective modification and incorporation into complex molecules.

Biochemical Research

It finds application in biochemical research for the synthesis of modified peptides or peptidomimetics. These can be used to study protein-ligand interactions or develop novel therapeutic agents.

02 /Properties

Molecular weight	569.65
Empirical formula	C37H31NO5
Assay	≥98.0%
Optical activity	[α]20/D +8.0±1°, c = 1% in DMF
Storage temperature	2-8°C
Melting point	200-210 °C (dec.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

111061-56-4

MDL number

MFCD00153364

Beilstein registry

5684859

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Ser(Trt)-OH primarily used for?

Fmoc-Ser(Trt)-OH is primarily used as a protected amino acid building block in solid-phase peptide synthesis (SPPS) and other organic synthesis applications.

What are the CAS number and molecular formula for Fmoc-Ser(Trt)-OH?

The CAS number is 111061-56-4, and the molecular formula is C37H31NO5.

What grade and purity does Tech Serve Solutions supply for Fmoc-Ser(Trt)-OH?

Tech Serve Solutions supplies Fmoc-Ser(Trt)-OH with an assay of ≥98.0%. This product is not represented as USP, BP, or EP grade.

How should Fmoc-Ser(Trt)-OH be handled and stored?

Handle Fmoc-Ser(Trt)-OH with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Store the material at 2-8°C to maintain its integrity.

Is Fmoc-Ser(Trt)-OH a controlled substance?

The provided data does not indicate that Fmoc-Ser(Trt)-OH is a controlled substance.

How is Fmoc-Ser(Trt)-OH packed, shipped, and exported by TSS?

Fmoc-Ser(Trt)-OH is carefully packed for stability and safety. As a global supplier, Tech Serve Solutions Ltd. has extensive experience in exporting chemicals worldwide, adhering to all relevant regulations.

How can I request a quote or sample for Fmoc-Ser(Trt)-OH?

To request a quote or a sample of Fmoc-Ser(Trt)-OH, please contact the Tech Serve Solutions sales team through our website or directly via email/phone.