5-Fluoro-2-nitrotoluene
5-Fluoro-2-nitrotoluene (CAS 446-33-3) is an organic compound with the formula CH3C6H3(NO2)F and a molecular weight of 155.13 g/mol. This fluorinated nitroaromatic compound serves as a valuable building block in organic synthesis. It is primarily utilised in the development of complex molecules within the pharmaceutical and agrochemical industries.

Pharmaceutical Intermediate
5-Fluoro-2-nitrotoluene is employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its specific chemical structure allows for versatile derivatisation in the development of novel therapeutic agents.
Agrochemical Synthesis
This compound finds application in the creation of novel agrochemicals, contributing to the development of effective crop protection agents. Its fluorinated nature can impart desirable properties to the final products.
Research and Development
As a functionalised aromatic building block, 5-Fluoro-2-nitrotoluene is widely used in academic and industrial research laboratories for exploring new synthetic pathways and discovering novel chemical entities.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | CH3C6H3(NO2)F |
| Assay | 97% |
| Boiling point | 97-98 °C/10 mmHg(lit.) |
| Density | 1.272 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.527(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 88 °C / 190.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-nitrotoluene used for?
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5-Fluoro-2-nitrotoluene is primarily used as a building block in organic synthesis, particularly for pharmaceutical intermediates and agrochemicals, as well as in research and development.
What are the CAS number and formula for 5-Fluoro-2-nitrotoluene?
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The CAS number for 5-Fluoro-2-nitrotoluene is 446-33-3, and its chemical formula is CH3C6H3(NO2)F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-nitrotoluene with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling requirements for 5-Fluoro-2-nitrotoluene?
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5-Fluoro-2-nitrotoluene is classified with GHS07 symbol and a Warning signal word. It carries hazard statements H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Always consult the Safety Data Sheet (SDS) before handling.
How is 5-Fluoro-2-nitrotoluene packed, shipped, and exported?
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Tech Serve Solutions meticulously packs and ships chemicals in compliance with international regulations. We are experienced exporters serving a global clientele.
How can I request a quote or sample for 5-Fluoro-2-nitrotoluene?
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To request a quote or sample of 5-Fluoro-2-nitrotoluene, please contact our sales team through the website or via the provided contact details.
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