2-Chloro-6-fluorophenylboronic acid
2-Chloro-6-fluorophenylboronic acid (CAS 313545-32-3) is an organoboron compound with the molecular formula C<sub>6</sub>H<sub>3</sub>ClFB(OH)<sub>2</sub> and a molecular weight of 174.37 g/mol. This aryl boronic acid serves as a key reactant in Suzuki coupling reactions and is utilised in the preparation of cellular checkpoint kinase Wee1 binding affectors. It is a valuable building block for organic synthesis in research and development.
Suzuki Coupling Reactions
2-Chloro-6-fluorophenylboronic acid is a versatile reagent for palladium-catalysed Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of complex biaryl compounds.
Preparation of Kinase Inhibitors
This compound is employed in the synthesis of molecules targeting cellular checkpoint kinase Wee1. Its specific structural features are integral to developing novel therapeutic agents.
Organic Synthesis Building Block
As a functionalised aryl boronic acid, it acts as a crucial intermediate in the multi-step synthesis of advanced organic molecules for research purposes.
| Molecular weight | 174.37 |
|---|---|
| Linear formula | C6H3ClFB(OH)2 |
| Application | Reactant for:• Suzuki coupling1• Preparation of cellular checkpoint kinase Wee1 binding affectors2 |
| Melting point | 131-135 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluorophenylboronic acid used for?
+
2-Chloro-6-fluorophenylboronic acid is primarily used as a reactant in Suzuki coupling reactions and for the preparation of cellular checkpoint kinase Wee1 binding affectors. It is a valuable building block in organic synthesis.
What are the CAS number and formula for 2-Chloro-6-fluorophenylboronic acid?
+
The CAS number for 2-Chloro-6-fluorophenylboronic acid is 313545-32-3, and its linear formula is C<sub>6</sub>H<sub>3</sub>ClFB(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are available on the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 2-Chloro-6-fluorophenylboronic acid be handled?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling and safety information. The product is classified under WGK 2 in Germany.
How is 2-Chloro-6-fluorophenylboronic acid packed and shipped?
+
This chemical is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for 2-Chloro-6-fluorophenylboronic acid?
+
To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through the website or by phone, referencing the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis