2-Chloro-6-fluorotoluene
2-Chloro-6-fluorotoluene (CAS 443-83-4), with the molecular formula C7H6ClF and a molar mass of 144.57 g/mol, is a halogenated aromatic compound. It serves as a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its specific arrangement of chloro and fluoro substituents on the toluene ring offers unique reactivity for complex molecular construction, making it an important intermediate for researchers and manufacturers in the chemical industry.
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates. The compound's structure allows for targeted functionalisation in drug discovery and development pipelines.
Agrochemical Synthesis
Serves as a precursor for various crop protection agents and pesticides. The incorporation of halogen atoms can enhance the efficacy and stability of agrochemical products.
Material Science Research
Investigated for its potential use in the development of novel materials. Its halogenated aromatic structure may impart specific electronic or physical properties.
Organic Synthesis Building Block
A versatile reagent for introducing the 2-chloro-6-fluorotolyl moiety into larger organic molecules. It is employed in complex multi-step syntheses across various chemical research fields.
| Molecular weight | 144.57 |
|---|---|
| Linear formula | CH3C6H3(Cl)F |
| Assay | 97% |
| Boiling point | 154-156 °C(lit.) |
| Density | 1.191 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 49 °C / 120.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-fluorotoluene primarily used for?
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2-Chloro-6-fluorotoluene is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and molecular formula for 2-Chloro-6-fluorotoluene?
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The CAS number is 443-83-4, and the molecular formula is CH3C6H3(Cl)F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-6-fluorotoluene with an assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Chloro-6-fluorotoluene be handled safely?
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2-Chloro-6-fluorotoluene is a flammable liquid and harmful if swallowed, inhaled, or in contact with skin. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. It has a flash point of 49°C (120.2°F).
Is 2-Chloro-6-fluorotoluene suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-6-fluorotoluene. We ensure compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloro-6-fluorotoluene, please contact our sales team through the website or by phone, providing your specific requirements.
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