3-Pyridinylboronic acid
3-Pyridinylboronic acid (CAS: 1692-25-7; Formula: C5H6BNO2; MW: 122.92) is a key organoboron compound supplied by Tech Serve Solutions. This heteroaryl boronic acid is a versatile building block in organic synthesis, particularly recognised for its utility in various palladium-catalyzed cross-coupling reactions. Its applications span the synthesis of complex organic molecules, including potential pharmaceutical intermediates and advanced materials.
- IUPAC
- 3-Pyridineboronic acid,3-Pyridylboronic acid,Dihydroxy(3-pyridyl)borane,Pyridin-3-ylboronic acid
- Synonyms
- 3-Pyridineboronic acid3-Pyridylboronic acidDihydroxy(3-pyridyl)boranePyridin-3-ylboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
3-Pyridinylboronic acid serves as a valuable coupling partner in Suzuki-Miyaura reactions, including those that are phosphine-free. It also facilitates regioselective couplings and tandem reactions.
N-Arylation Reactions
This boronic acid derivative can be employed in N-arylation reactions catalysed by copper acetylacetonate, contributing to the formation of C-N bonds.
Synthesis of Advanced Materials
It is used in the preparation of novel linear poly(phenylpyridyl) chains and oligopyridyl foldamers, finding applications in materials science and supramolecular chemistry.
Preparation of Pharmaceutical Intermediates
3-Pyridinylboronic acid is instrumental in the synthesis of various significant therapeutic agents, including enzyme inhibitors and receptor antagonists.
| Molecular weight | 122.92 |
|---|---|
| Empirical formula | C5H6BNO2 |
| Assay | ≥95.0% |
| Application | Reagent used for• Phosphine-free Suzuki-Miyaura cross-coupling reactions1 • Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation2 • N-arylation using copper acetylacetonate catalyst3 • Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes4 Reagent use in Preparation of • New linear poly(phenylpyridyl) chains by Suzuki coupling5 • Oligopyridyl foldamers as mimics of a-helix twist6 • Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists7,8,9 |
| Melting point | >300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Pyridinylboronic acid used for?
+
3-Pyridinylboronic acid is used as a reagent in various organic synthesis applications, including phosphine-free Suzuki-Miyaura cross-coupling reactions, N-arylation, and the preparation of advanced materials and potential pharmaceutical intermediates.
What are the CAS number and formula for 3-Pyridinylboronic acid?
+
The CAS number for 3-Pyridinylboronic acid is 1692-25-7, and its molecular formula is C5H6BNO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Pyridinylboronic acid with an assay of ≥95.0%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product specifications.
What are the safety and handling considerations for 3-Pyridinylboronic acid?
+
Handling 3-Pyridinylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is a risk. It is classified with a WGK Germany of 3, indicating it is hazardous to water.
How is 3-Pyridinylboronic acid shipped and exported?
+
Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, ensuring products are packed and shipped in compliance with all relevant international regulations for safe transport.
How can I request a sample or quote for 3-Pyridinylboronic acid?
+
To request a sample or a quote for 3-Pyridinylboronic acid, please contact our sales department through the details provided on the Tech Serve Solutions website.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis