Fmoc-Tyr(3,5-I2)-OH
Fmoc-Tyr(3,5-I2)-OH (CAS: 103213-31-6), a diiodinated derivative of L-tyrosine, features the Fmoc protecting group for controlled peptide synthesis. With a molecular weight of 655.22 g/mol and empirical formula C24H19I2NO5, this compound is a valuable building block in chemical biology and peptide chemistry research. It is primarily utilised for the incorporation of unnatural amino acids into peptides, enabling the study of protein structure and function.
- IUPAC
- Fmoc-3,5-diiodo-L-tyrosine
- Synonyms
- Fmoc-3,5-diiodo-L-tyrosineN-",(Fmoc)O-",3',5'-DiiodotyrosineFmoc-L-tyrosine, 3',5'-diiodo-
Peptide Synthesis
Used as a protected amino acid building block in solid-phase or solution-phase peptide synthesis. The Fmoc group allows for orthogonal deprotection strategies in constructing complex peptide sequences.
Chemical Biology
Incorporated into peptides to create modified structures for investigating protein-protein interactions, enzyme mechanisms, or as labelled probes in biological systems.
Medicinal Chemistry Research
Serves as a precursor for developing novel therapeutic peptides or peptidomimetics, where the iodine substituents can influence pharmacokinetic properties or act as radiolabels.
Bioconjugation
The modified tyrosine residue can be used in bioconjugation strategies to attach peptides to other molecules, such as proteins, nanoparticles, or surfaces.
| Molecular weight | 655.22 |
|---|---|
| Empirical formula | C24H19I2NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Tyr(3,5-I2)-OH used for?
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Fmoc-Tyr(3,5-I2)-OH is primarily used as a specialised building block in peptide synthesis, particularly for incorporating unnatural amino acid residues into peptide chains for research in chemical biology, medicinal chemistry, and proteomics.
What are the CAS number and empirical formula for Fmoc-Tyr(3,5-I2)-OH?
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The CAS number is 103213-31-6, and the empirical formula is C24H19I2NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Tyr(3,5-I2)-OH with an assay of ≥98.0% (HPLC). This is suitable for research and development purposes. It is not supplied as USP, BP, or EP grade.
How should Fmoc-Tyr(3,5-I2)-OH be handled and stored?
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Handle Fmoc-Tyr(3,5-I2)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store at 2-8°C to maintain product integrity. Dispose of in accordance with local regulations.
Is Fmoc-Tyr(3,5-I2)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Tyr(3,5-I2)-OH is a controlled substance.
How is this product shipped?
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Fmoc-Tyr(3,5-I2)-OH is typically shipped under controlled temperature conditions. As a global supplier, Tech Serve Solutions ensures compliant and secure export procedures.
How can I request a sample or quote for Fmoc-Tyr(3,5-I2)-OH?
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To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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