Fmoc-Tyr(3-NO2)-OH
Fmoc-3-nitro-L-tyrosine (CAS: 136590-09-5), with the molecular formula C24H20N2O7 and a molecular weight of 448.42 g/mol, is a protected unnatural amino acid derivative. It features the Fmoc protecting group on the amine nitrogen and a nitro group on the tyrosine side chain. This compound is primarily utilised in solid-phase peptide synthesis and for the introduction of modified tyrosine residues into peptide sequences.
- IUPAC
- Fmoc-3-nitro-L-tyrosine
- Synonyms
- Fmoc-3-nitro-L-tyrosine
Peptide Synthesis
Fmoc-3-nitro-L-tyrosine is a key building block in solid-phase peptide synthesis (SPPS), enabling the incorporation of nitro-tyrosine into peptide chains. This modification can be used for various purposes, including the synthesis of peptide analogues or as a precursor for further chemical transformations.
Chemical Biology Research
This unnatural amino acid derivative is employed in chemical biology to create peptides with altered properties or functionalities. The nitro group can serve as a spectroscopic probe or a reactive handle for bioconjugation or other chemical modifications.
Synthesis of Modified Peptides
Researchers utilise Fmoc-3-nitro-L-tyrosine to synthesise peptides containing modified tyrosine residues. The nitro group can be reduced to an amino group, allowing for further derivatisation and the creation of diverse peptide structures for various applications.
| Molecular weight | 448.42 |
|---|---|
| Empirical formula | C24H20N2O7 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-3-nitro-L-tyrosine used for?
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Fmoc-3-nitro-L-tyrosine is used as a building block in solid-phase peptide synthesis and chemical biology research to introduce modified tyrosine residues into peptide sequences.
What is the CAS number and formula for Fmoc-3-nitro-L-tyrosine?
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The CAS number for Fmoc-3-nitro-L-tyrosine is 136590-09-5, and its molecular formula is C24H20N2O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-3-nitro-L-tyrosine with an assay of ≥97.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-3-nitro-L-tyrosine?
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When handling Fmoc-3-nitro-L-tyrosine, it is recommended to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. The compound is classified under WGK Germany 3.
How is Fmoc-3-nitro-L-tyrosine packed, shipped, and exported?
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Fmoc-3-nitro-L-tyrosine is typically stored at 2-8°C. Tech Serve Solutions ensures careful packaging for secure transport and export worldwide.
How can I request a sample or quote for Fmoc-3-nitro-L-tyrosine?
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To request a sample or obtain a quote for Fmoc-3-nitro-L-tyrosine, please contact our sales team through the website or by direct inquiry.
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