Fmoc-Tyr(PO3Me2)-OH

CAS 127633-36-7C26H26NO8PChemical Synthesis

Fmoc-Tyr(PO3Me2)-OH (CAS: 127633-36-7) is a protected amino acid derivative with the molecular formula C26H26NO8P and a molecular weight of 511.46 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. Its structure features a phosphodiester modification on the tyrosine side chain, making it valuable for investigating post-translational modifications and developing novel peptide-based therapeutics. It is supplied by Tech Serve Solutions for research and development purposes.

IUPAC: Fmoc-O-(dimethylphospho)-L-tyrosine
Synonyms: Fmoc-O-(dimethylphospho)-L-tyrosine

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Fmoc-Tyr(PO3Me2)-OH (C26H26NO8P) — chemical structure, CAS 127633-36-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAnalytical StandardsAnalytical/ChromatographyChemical BiologyChemical SynthesisFM - FZPeptide ChemistryTyrosine More...

01 /Applications

Peptide Synthesis

This Fmoc-protected tyrosine derivative is instrumental in the solid-phase or solution-phase synthesis of peptides containing phosphotyrosine mimetic residues. It allows for the controlled incorporation of modified amino acids into peptide chains.

Chemical Biology Research

Used to study the biological roles and signalling pathways involving phosphorylated tyrosine residues. Its incorporation into peptides can help elucidate enzyme mechanisms or protein-protein interactions.

Drug Discovery and Development

Serves as a building block for the synthesis of novel peptide therapeutics or diagnostic agents. The phosphodiester moiety can influence pharmacokinetic properties or target binding affinity.

02 /Properties

Molecular weight	511.46
Empirical formula	C26H26NO8P
Assay	≥96.0%
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

127633-36-7

MDL number

MFCD00133599

Beilstein registry

4620821

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Tyr(PO3Me2)-OH used for?

Fmoc-Tyr(PO3Me2)-OH is primarily used in peptide synthesis and chemical biology research for the incorporation of modified tyrosine residues, particularly those mimicking phosphorylated tyrosine, into peptide structures.

What are the CAS number and formula for Fmoc-Tyr(PO3Me2)-OH?

The CAS number is 127633-36-7 and the empirical formula is C26H26NO8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Tyr(PO3Me2)-OH with an assay of ≥96.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling requirements for this compound?

This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used when handling. It has a WGK rating of 3 in Germany, indicating a high hazard level.

How is Fmoc-Tyr(PO3Me2)-OH shipped and exported?

This chemical is stored at 2-8°C and is carefully packaged and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for fine chemicals.