Fmoc-Tyr-OH
Fmoc-Tyr-OH (CAS 92954-90-0), a derivative of L-tyrosine with the molecular formula C24H21NO5 and a molecular weight of 403.43 g/mol, is a crucial building block in peptide synthesis. Its Nα-Fmoc protection facilitates sequential amino acid coupling in solid-phase peptide synthesis (SPPS). This compound is widely employed in chemical biology and synthesis for constructing peptides with specific biological functions.
- IUPAC
- Nα-Fmoc-L-tyrosine
- Synonyms
- Nα-Fmoc-L-tyrosine
Peptide Synthesis
Fmoc-Tyr-OH serves as a key protected amino acid in the Fmoc/tBu solid-phase peptide synthesis strategy. Its N-terminal Fmoc group allows for controlled deprotection and sequential coupling of amino acids to build complex peptide chains.
Chemical Biology Research
In chemical biology, Fmoc-Tyr-OH is utilised to synthesise peptides that mimic or modulate biological processes. Its incorporation can introduce specific functionalities or structural motifs into peptides for studying protein-ligand interactions or enzyme mechanisms.
Organic Synthesis
As a protected amino acid derivative, Fmoc-Tyr-OH is a valuable reagent in general organic synthesis, particularly for constructing molecules containing tyrosine residues with orthogonal protection strategies.
| Molecular weight | 403.43 |
|---|---|
| Empirical formula | C24H21NO5 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/D −22±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Tyr-OH used for?
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Fmoc-Tyr-OH is primarily used as a protected amino acid building block in Fmoc-based solid-phase peptide synthesis and in various chemical biology and organic synthesis applications.
What is the CAS number and chemical formula for Fmoc-Tyr-OH?
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The CAS number for Fmoc-Tyr-OH is 92954-90-0 and its chemical formula is C24H21NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Tyr-OH with a purity of ≥97.0% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Tyr-OH be handled and stored?
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Fmoc-Tyr-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store in a refrigerator at 2-8°C.
Is Fmoc-Tyr-OH a controlled substance?
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The provided data does not indicate that Fmoc-Tyr-OH is a controlled substance.
How can I request a sample or quote for Fmoc-Tyr-OH?
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Please contact the Tech Serve Solutions sales team via our website or direct contact details to request a sample or a quotation for Fmoc-Tyr-OH.
How is Fmoc-Tyr-OH shipped and exported?
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Fmoc-Tyr-OH is carefully packed for shipping and export in accordance with relevant regulations to ensure safe and secure delivery globally.
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