Fmoc-allyl-Gly-OH
Fmoc-allyl-Gly-OH (CAS: 146549-21-5), with the molecular formula C20H19NO4 and a molecular weight of 337.37, is an unnatural amino acid derivative crucial for advanced peptide synthesis. Its structure incorporates both the Fmoc protecting group and a reactive allyl side chain, enabling controlled peptide elongation and subsequent orthogonal deprotection strategies in complex biomolecule research and development.
- IUPAC
- (S)-2-(Fmoc-amino)-4-pentenoic acid,Fmoc-L-2-allylglycine
Peptide Synthesis
Utilised as a building block in solid-phase or solution-phase peptide synthesis, particularly for incorporating unnatural amino acids into peptide chains to study their structure-activity relationships or to create novel peptidomimetics.
Chemical Biology Research
Employed in the synthesis of modified peptides for investigating protein-ligand interactions, enzyme mechanisms, or developing peptide-based therapeutics, where specific side-chain modifications are required.
Drug Discovery and Development
Serves as a key intermediate in the synthesis of novel drug candidates and complex pharmaceutical molecules that require precise incorporation of non-proteinogenic amino acid residues.
Bioconjugation Strategies
The allyl group can be used for post-synthetic modification or conjugation to other biomolecules or surfaces via allyl-specific reactions, expanding the utility of the synthesized peptides.
| Molecular weight | 337.37 |
|---|---|
| Empirical formula | C20H19NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-allyl-Gly-OH used for?
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Fmoc-allyl-Gly-OH is primarily used as an unnatural amino acid building block in peptide synthesis, chemical biology research, and drug discovery, especially when precise side-chain modifications and orthogonal deprotection strategies are needed.
What is the CAS number and chemical formula for Fmoc-allyl-Gly-OH?
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The CAS number is 146549-21-5, and the empirical formula (Hill notation) is C20H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-allyl-Gly-OH with an assay of ≥98.0% as determined by HPLC. This product is typically intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-allyl-Gly-OH be stored and handled?
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Fmoc-allyl-Gly-OH should be stored at 2-8°C. When handling, ensure adequate personal protective equipment, including eyeshields and gloves, and use a P1 (EN143) or N95 (US) respirator filter if airborne exposure is possible, given its classification (WGK Germany 3).
Is this chemical a controlled substance?
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The provided data does not indicate that Fmoc-allyl-Gly-OH (CAS: 146549-21-5) is a controlled substance.
How are your chemicals packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and compliance with international shipping regulations for research reagents and intermediates.
How can I request a sample or a quote for Fmoc-allyl-Gly-OH?
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You can request a sample or obtain a quote for Fmoc-allyl-Gly-OH by contacting our sales team through the designated channels on the Tech Serve Solutions website.
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