Fmoc-leu-bt
Fmoc-leu-bt (CAS: 1072840-99-3) is a benzotriazole amino acid derivative with the molecular formula C27H26N4O3. This compound serves as a versatile reagent in peptide synthesis, enabling the creation of complex molecules such as peptidomimetics and conjugates. Its chemical structure facilitates efficient coupling reactions, making it valuable in chemical biology and advanced organic synthesis.
- IUPAC
- (S)-(9H-Fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate,(S)-N-Fmoc-1-benzotriazolylcarbonyl-3-methylbutylamine
Peptide Synthesis
Fmoc-leu-bt is employed in the solid-phase and solution-phase synthesis of peptides. It acts as an activated amino acid building block, facilitating the formation of peptide bonds with high efficiency.
Peptidomimetic Preparation
This reagent is utilized for the synthesis of peptidomimetics, which are compounds that mimic the structure and function of natural peptides but often possess enhanced stability or altered pharmacological properties.
Synthesis of Conjugates
Fmoc-leu-bt can be used to prepare peptide and peptidomimetic conjugates, linking them to other molecules, such as fluorescent labels or other functional groups, for various research applications.
Chemical Biology Research
Its utility extends to chemical biology, where it aids in constructing modified peptides and probes for studying biological systems and processes.
| Molecular weight | 454.52 |
|---|---|
| Empirical formula | C27H26N4O3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:• Polypeptidal benzotriazolides1• Peptidomimetics, such as aminoxypeptides2, depsipeptides3 and heterocyclic peptidomimetics4• Tagged peptides and peptidomimetics, particularly those with fluorescent labels5,6• N, O, S, and C linked peptide conjugates6 |
| Melting point | 121-126 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-leu-bt used for?
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Fmoc-leu-bt is used as a versatile reagent in peptide synthesis, for the preparation of peptidomimetics, and for creating peptide and peptidomimetic conjugates. It is valuable in chemical biology and chemical synthesis.
What is the CAS number and formula for Fmoc-leu-bt?
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The CAS number for Fmoc-leu-bt is 1072840-99-3, and its empirical formula is C27H26N4O3.
What grade and purity does Tech Serve Solutions supply for Fmoc-leu-bt?
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Tech Serve Solutions supplies Fmoc-leu-bt with a typical purity of 97%. This product is intended for research and laboratory use. We do not represent it as USP, BP, or EP grade.
How should Fmoc-leu-bt be stored and handled?
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Fmoc-leu-bt should be stored at 2-8°C. As with many laboratory chemicals, handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure.
How is Fmoc-leu-bt shipped by TSS?
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Tech Serve Solutions exports and ships fine chemicals globally, adhering to all necessary regulations for safe and compliant transport of laboratory reagents.
How can I request a sample or quote for Fmoc-leu-bt?
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To request a sample or a quotation for Fmoc-leu-bt, please contact our sales team through the website or by phone.
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