Fmoc-α-Me-Ala-OH
Fmoc-α-Me-Ala-OH (CAS 94744-50-0) is a protected unnatural amino acid derivative with the empirical formula C19H19NO4 and a molecular weight of 325.36 g/mol. As an alanine derivative, it is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its Fmoc protection group facilitates controlled peptide chain elongation.
- IUPAC
- Fmoc-α-aminoisobutyric acid,Fmoc-α-methylalanine
- Synonyms
- Fmoc-α-aminoisobutyric acidFmoc-α-methylalanine

Peptide Synthesis
This Fmoc-protected amino acid is a valuable building block for solid-phase and solution-phase peptide synthesis. Its unnatural alpha-methyl substitution can introduce conformational constraints or improve metabolic stability in resulting peptides.
Chemical Biology Research
Used in the design and synthesis of modified peptides for studying biological processes. Its incorporation can lead to peptidomimetics with altered receptor binding or enzymatic resistance.
Organic Synthesis
Serves as a chiral building block in the synthesis of complex organic molecules. The protected amino acid moiety can be elaborated using various synthetic methodologies.
| Molecular weight | 325.36 |
|---|---|
| Empirical formula | C19H19NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 182-188 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-α-Me-Ala-OH used for?
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Fmoc-α-Me-Ala-OH is primarily used as a building block in peptide synthesis, chemical biology research, and organic synthesis. It is particularly useful for creating modified peptides with enhanced properties.
What are the CAS number and formula for Fmoc-α-Me-Ala-OH?
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The CAS number is 94744-50-0, and the empirical formula is C19H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-α-Me-Ala-OH with a purity of ≥97.0% (HPLC). This product is suitable for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Fmoc-α-Me-Ala-OH be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. The compound should be stored at 2-8°C.
Is Fmoc-α-Me-Ala-OH a controlled substance?
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Based on the provided data, there is no indication that Fmoc-α-Me-Ala-OH is a controlled substance.
How is Fmoc-α-Me-Ala-OH packed, shipped, and exported?
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Fmoc-α-Me-Ala-OH is packed and shipped according to standard laboratory chemical protocols to maintain product integrity. Tech Serve Solutions is a specialist global supplier and exporter.
How can I request a sample or quote for Fmoc-α-Me-Ala-OH?
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To request a sample or a quote for Fmoc-α-Me-Ala-OH, please contact our sales team through the website or by telephone.
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