Fmoc-β-(2-furyl)-D-Ala-OH
Fmoc-β-(2-furyl)-D-Ala-OH (CAS: 220497-85-8) is a valuable unnatural amino acid derivative with the molecular formula C22H19NO5 and a molecular weight of 377.39 g/mol. It features the Fmoc protecting group, an alanine backbone substituted with a furan ring, and a carboxylic acid moiety. This compound is primarily utilised in peptide chemistry and chemical synthesis for the incorporation of non-canonical amino acids into peptide chains, enabling the exploration of novel structures and functionalities.
- IUPAC
- (R)-2-(Fmoc-amino)-3-(2-furyl)propionicacid,Fmoc-3-(2-furyl)-D-alanine
- Synonyms
- Fmoc-3-(2-furyl)-D-alanine(R)-2-(Fmoc-amino)-3-(2-furyl)propionicacid

Peptide Synthesis
Serves as a building block in solid-phase and solution-phase peptide synthesis for incorporating unnatural amino acids. Its unique structure can impart specific conformational properties or functionalities to the resulting peptides.
Chemical Biology
Utilised in the design and synthesis of modified peptides for studying biological processes. The furan moiety can participate in various chemical reactions or interactions, offering avenues for bioconjugation or probe development.
Drug Discovery
Acts as an intermediate in the synthesis of novel pharmaceutical candidates. Incorporating unnatural amino acids like Fmoc-β-(2-furyl)-D-Ala-OH can lead to improved pharmacokinetic profiles or enhanced biological activity of drug molecules.
Materials Science
Can be employed in the development of peptide-based biomaterials or functional polymers. The furan group offers potential for cross-linking or further functionalization in material design.
| Molecular weight | 377.39 |
|---|---|
| Empirical formula | C22H19NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(2-furyl)-D-Ala-OH used for?
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Fmoc-β-(2-furyl)-D-Ala-OH is primarily used as a building block in peptide synthesis and chemical biology for incorporating unnatural amino acids, contributing to the creation of novel peptides, peptidomimetics, and related compounds with tailored properties for research and drug discovery.
What is the CAS number and chemical formula for Fmoc-β-(2-furyl)-D-Ala-OH?
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The CAS number for Fmoc-β-(2-furyl)-D-Ala-OH is 220497-85-8, and its molecular formula is C22H19NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(2-furyl)-D-Ala-OH with a purity of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-β-(2-furyl)-D-Ala-OH be handled and stored?
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Handle Fmoc-β-(2-furyl)-D-Ala-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store the compound at 2-8°C.
Is this compound a controlled substance?
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The provided data does not indicate that Fmoc-β-(2-furyl)-D-Ala-OH is a controlled substance.
How are products from Tech Serve Solutions packed, shipped, and exported?
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Tech Serve Solutions specialises in global supply and export, ensuring products are appropriately packed to maintain integrity during transit. Specific packaging details vary based on product and destination.
How can I request a sample or quote?
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To request a sample or quote for Fmoc-β-(2-furyl)-D-Ala-OH, please contact our sales department through the channels provided on the Tech Serve Solutions website.
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