Fmoc-β-(2-pyridyl)-D-Ala-OH
Fmoc-β-(2-pyridyl)-D-Ala-OH (CAS: 185379-39-9) is a modified D-alanine derivative featuring a 2-pyridyl substituent and Fmoc protection. With a molecular formula of C23H20N2O4 and a molecular weight of 388.42 g/mol, this compound is primarily employed in peptide synthesis and chemical biology research. Its unique structure allows for the incorporation of pyridyl functionality into peptides, facilitating studies in areas like metal coordination and drug delivery.
- IUPAC
- Fmoc-3-(2-pyridyl)-D-alanine
- Synonyms
- Fmoc-3-(2-pyridyl)-D-alanine

Peptide Synthesis
This Fmoc-protected unnatural amino acid is used to introduce pyridyl side chains into peptide sequences during solid-phase or solution-phase synthesis. It enables the construction of peptides with novel functionalities for biochemical or medicinal chemistry studies.
Chemical Biology Research
The pyridyl moiety can act as a ligand for metal ions or influence peptide conformation and interactions. Researchers utilize Fmoc-β-(2-pyridyl)-D-Ala-OH to develop probes, peptidomimetics, or modified proteins for biological investigations.
Organic Synthesis
As a building block, this derivative can be employed in the synthesis of complex organic molecules and heterocyclic compounds. The protected amino acid functionality and the pyridyl group offer versatile reaction handles.
| Molecular weight | 388.42 |
|---|---|
| Empirical formula | C23H20N2O4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(2-pyridyl)-D-Ala-OH used for?
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Fmoc-β-(2-pyridyl)-D-Ala-OH is primarily used in peptide synthesis and chemical biology research. Its structure allows for the incorporation of a pyridyl group into peptide chains, enabling the study of metal coordination, modified peptide structures, and biological interactions.
What is the CAS number and formula for Fmoc-β-(2-pyridyl)-D-Ala-OH?
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The CAS number is 185379-39-9, and the empirical formula (Hill notation) is C23H20N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(2-pyridyl)-D-Ala-OH with an assay of ≥98.0% (HPLC). This product is intended for research and technical use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-β-(2-pyridyl)-D-Ala-OH be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter may be necessary. Store at 2-8°C to maintain product integrity. This compound is classified under WGK Germany 3.
Is this product controlled or scheduled?
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The provided data does not indicate that Fmoc-β-(2-pyridyl)-D-Ala-OH is a controlled or scheduled substance.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or obtain a quotation for Fmoc-β-(2-pyridyl)-D-Ala-OH.
How is this chemical shipped?
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Tech Serve Solutions exports fine chemicals globally. Shipping conditions are optimised to maintain product stability and comply with international regulations.
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