Fmoc-β-(3-pyridyl)-D-Ala-OH

CAS 142994-45-4C23H20N2O4Chemical Synthesis

Fmoc-β-(3-pyridyl)-D-Ala-OH (CAS: 142994-45-4), with the molecular formula C23H20N2O4 and a molecular weight of 388.42 g/mol, is a specialised unnatural amino acid derivative. It is a valuable building block in peptide chemistry and organic synthesis. This compound is typically employed in research settings for the construction of novel peptides and complex organic molecules, contributing to advancements in chemical biology and drug discovery.

IUPAC: Fmoc-3-(3-pyridyl)-D-alanine
Synonyms: Fmoc-3-(3-pyridyl)-D-alanine

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Fmoc-β-(3-pyridyl)-D-Ala-OH (C23H20N2O4) — chemical structure, CAS 142994-45-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Alanine DerivativesChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis to introduce a pyridyl-alanine moiety into peptide sequences. This modification can alter peptide conformation, stability, or biological activity.

Chemical Biology Research

Employed in the development of peptides with specific biological functions or as tools for studying protein-ligand interactions. The pyridine ring offers potential for metal coordination or altered binding characteristics.

Organic Synthesis Intermediate

Serves as a chiral building block for the synthesis of complex organic molecules where the pyridyl-alanine structure is a key feature. Its protected nature facilitates controlled multi-step synthetic routes.

02 /Properties

Molecular weight	388.42
Empirical formula	C23H20N2O4
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

142994-45-4

MDL number

MFCD00080267

Beilstein registry

9223259

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-β-(3-pyridyl)-D-Ala-OH used for?

Fmoc-β-(3-pyridyl)-D-Ala-OH is primarily used as a protected unnatural amino acid in peptide synthesis and as a building block in organic synthesis for chemical biology research.

What is the CAS number and molecular formula?

The CAS number is 142994-45-4 and the molecular formula is C23H20N2O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-β-(3-pyridyl)-D-Ala-OH with an assay of ≥98.0% (HPLC). This product is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling recommendations?

Handle Fmoc-β-(3-pyridyl)-D-Ala-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Observe standard laboratory safety protocols when handling this compound.

How is this chemical shipped?

This chemical is typically stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging and documentation for international shipments.