Fmoc-β-(4-pyridyl)-D-Ala-OH
Fmoc-β-(4-pyridyl)-D-Ala-OH (CAS: 205528-30-9) is a protected unnatural amino acid derivative with the empirical formula C23H20N2O4 and a molecular weight of 388.42 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its structure allows for the incorporation of a pyridine moiety into peptide chains, enabling the study of modified peptides and the development of novel biomaterials.
- IUPAC
- Fmoc-3-(4-pyridyl)-D-alanine

Peptide Synthesis
Fmoc-β-(4-pyridyl)-D-Ala-OH is employed as a protected amino acid in solid-phase or solution-phase peptide synthesis. Its unique pyridine side chain can introduce specific functionalities and binding capabilities into peptide sequences.
Chemical Biology Research
This unnatural amino acid derivative is utilized in chemical biology to create peptides with altered structures and properties. It can be used to probe protein-ligand interactions or to develop novel peptide-based probes.
Drug Discovery and Development
Incorporating pyridine-containing amino acids can influence the pharmacokinetic and pharmacodynamic properties of peptide-based therapeutics. Fmoc-β-(4-pyridyl)-D-Ala-OH offers a route to explore such modifications.
Material Science
The pyridine group can participate in coordination chemistry or supramolecular assembly, making peptides containing this residue potentially useful in the design of functional materials.
| Molecular weight | 388.42 |
|---|---|
| Empirical formula | C23H20N2O4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(4-pyridyl)-D-Ala-OH used for?
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Fmoc-β-(4-pyridyl)-D-Ala-OH is primarily used as a building block in peptide synthesis, chemical biology research, drug discovery, and material science due to its unnatural amino acid structure with a pyridine side chain.
What is the CAS number and formula for Fmoc-β-(4-pyridyl)-D-Ala-OH?
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The CAS number is 205528-30-9, and the empirical formula is C23H20N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(4-pyridyl)-D-Ala-OH with an assay of ≥98.0%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Fmoc-β-(4-pyridyl)-D-Ala-OH be stored and handled?
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This compound should be stored at 2-8°C. When handling, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. Note that it has a WGK Germany rating of 3.
Does Tech Serve Solutions export Fmoc-β-(4-pyridyl)-D-Ala-OH?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Fmoc-β-(4-pyridyl)-D-Ala-OH.
How can I request a sample or quote for Fmoc-β-(4-pyridyl)-D-Ala-OH?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number (205528-30-9).
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