Fmoc-β-(3-thienyl)-Ala-OH
Fmoc-β-(3-thienyl)-Ala-OH (CAS 186320-06-9) is a protected, unnatural amino acid derivative with the molecular formula C22H19NO4S and a molecular weight of 393.46 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research, serving as a building block for the creation of novel peptides and modified biomolecules. Its structure incorporates a thienyl group, offering unique properties for incorporation into peptide chains.
- IUPAC
- (S)-2-(Fmoc-amino)-3-(3-thienyl)propionic acid,Fmoc-3-(3-thienyl)-L-alanine
- Synonyms
- (S)-2-(Fmoc-amino)-3-(3-thienyl)propionic acidFmoc-3-(3-thienyl)-L-alanine

Peptide Synthesis
Utilised as a protected unnatural amino acid in solid-phase and solution-phase peptide synthesis. It allows for the introduction of a thienylalanine residue into peptide sequences, modifying their structure and properties.
Chemical Biology Research
Serves as a valuable tool for researchers investigating structure-activity relationships and developing novel peptide-based therapeutics or probes. The thienyl moiety can influence peptide folding, binding, and stability.
Drug Discovery and Development
Incorporated into peptidomimetics and small molecules during the early stages of drug discovery. The unnatural amino acid structure can enhance metabolic stability or target specific biological pathways.
Materials Science
May be employed in the synthesis of novel biomaterials or functional polymers where the thienyl group can impart specific electronic or structural characteristics.
| Molecular weight | 393.46 |
|---|---|
| Empirical formula | C22H19NO4S |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(3-thienyl)-Ala-OH used for?
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Fmoc-β-(3-thienyl)-Ala-OH is used in peptide synthesis and chemical biology research as a protected unnatural amino acid building block for creating novel peptides and modified biomolecules.
What are the CAS number and formula for Fmoc-β-(3-thienyl)-Ala-OH?
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The CAS number is 186320-06-9, and the empirical formula is C22H19NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(3-thienyl)-Ala-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Fmoc-β-(3-thienyl)-Ala-OH be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection such as a type N95 (US) or P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-β-(3-thienyl)-Ala-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-(3-thienyl)-Ala-OH is a controlled substance. For specific regulatory information, please consult your local authorities.
How is this chemical packed, shipped, and exported?
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Fmoc-β-(3-thienyl)-Ala-OH is carefully packed to ensure stability and safety during transit. Tech Serve Solutions, as a global supplier, adheres to international shipping regulations for chemical exports.
How can I request a sample or quote for Fmoc-β-(3-thienyl)-Ala-OH?
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To request a sample or a quotation, please contact our sales team directly through the website or provide your details via the enquiry form, specifying your interest in Fmoc-β-(3-thienyl)-Ala-OH (CAS 186320-06-9).
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