Fmoc-β-(4-pyridyl)-Ala-OH
Fmoc-β-(4-pyridyl)-Ala-OH (CAS: 169555-95-7) is a protected unnatural amino acid derivative with the molecular formula C23H20N2O4. This compound is valuable in chemical synthesis and peptide chemistry, particularly for incorporating modified alanine residues into peptides. Its Fmoc protecting group facilitates controlled peptide chain elongation in solid-phase synthesis, while the 4-pyridyl side chain offers unique structural and functional properties for further modification or interaction.
- IUPAC
- Fmoc-3-(4-pyridyl)-L-alanine

Peptide Synthesis
Fmoc-β-(4-pyridyl)-Ala-OH serves as a key building block in solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Its incorporation allows for the introduction of a pyridyl-modified alanine residue, expanding the structural diversity of synthesized peptides.
Chemical Biology Research
This unnatural amino acid derivative can be utilized in chemical biology to create peptides with altered functionalities. The pyridyl group may be involved in metal coordination, hydrogen bonding, or serving as a site for subsequent chemical transformations.
Drug Discovery and Development
Incorporating modified amino acids like Fmoc-β-(4-pyridyl)-Ala-OH into peptide sequences can modulate pharmacokinetic properties, receptor binding, or introduce novel functionalities relevant to pharmaceutical research and the development of new therapeutics.
Materials Science
The presence of the pyridine ring offers potential for applications in materials science, such as the development of functionalized polymers or self-assembling peptide-based materials where the pyridine moiety can interact with metal ions or surfaces.
| Molecular weight | 388.42 |
|---|---|
| Empirical formula | C23H20N2O4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(4-pyridyl)-Ala-OH used for?
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Fmoc-β-(4-pyridyl)-Ala-OH is primarily used in peptide synthesis as a protected unnatural amino acid building block, for chemical biology research, and in drug discovery to introduce modified alanine residues into peptide sequences.
What are the CAS number and molecular formula of Fmoc-β-(4-pyridyl)-Ala-OH?
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The CAS number is 169555-95-7, and the molecular formula is C23H20N2O4.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-(4-pyridyl)-Ala-OH?
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Tech Serve Solutions supplies Fmoc-β-(4-pyridyl)-Ala-OH with an assay of ≥97.0% (HPLC). This product is intended for research and laboratory use.
How should Fmoc-β-(4-pyridyl)-Ala-OH be handled and stored?
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This compound should be handled with appropriate personal protective equipment, including eyeshields and gloves. Recommended storage is at 2-8°C. Ensure good ventilation during handling. The German WGK classification is 3, indicating a high hazard to water.
Is Fmoc-β-(4-pyridyl)-Ala-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-(4-pyridyl)-Ala-OH is a controlled substance.
How is Fmoc-β-(4-pyridyl)-Ala-OH packed, shipped, and exported?
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Fmoc-β-(4-pyridyl)-Ala-OH is carefully packed and exported by Tech Serve Solutions in compliance with all relevant shipping regulations for fine chemicals, ensuring product integrity and safety during transit.
How can I request a sample or quote for Fmoc-β-(4-pyridyl)-Ala-OH?
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To request a sample or a quote for Fmoc-β-(4-pyridyl)-Ala-OH, please contact the Tech Serve Solutions sales team through our website or by phone, providing your contact details and the product CAS number (169555-95-7).
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