Fmoc-β-D-Phe-OH
Fmoc-β-D-Phe-OH (CAS: 209252-15-3) is a white to off-white solid with the molecular formula C24H21NO4 and a molecular weight of 387.43 g/mol. This unnatural beta-amino acid derivative, protected with the Fmoc group, is a valuable building block in chemical synthesis. It finds applications in peptide chemistry and chemical biology research, enabling the construction of complex peptides and peptidomimetics with unique structural and functional properties.
- IUPAC
- (S)-3-(Fmoc-amino)-3-phenylpropionic acid,Fmoc-D-β-phenylalanine
Peptide Synthesis
Fmoc-β-D-Phe-OH serves as a key intermediate in the synthesis of peptides containing unnatural beta-amino acids. Its incorporation allows for the creation of peptides with altered conformational stability and biological activity compared to their natural counterparts.
Chemical Biology Research
This compound is utilised in chemical biology to develop novel probes and modified biomolecules. The unique structure of beta-phenylalanine can be leveraged to study protein-protein interactions or to engineer enzymes with tailored functions.
Drug Discovery and Development
As an unnatural amino acid derivative, Fmoc-β-D-Phe-OH can be incorporated into peptidomimetics for drug discovery programs. This can lead to compounds with improved pharmacokinetic profiles, such as increased resistance to enzymatic degradation.
Custom Synthesis Projects
Researchers undertaking custom synthesis projects requiring specific beta-amino acid building blocks can utilise Fmoc-β-D-Phe-OH. Its protected nature and defined stereochemistry make it suitable for complex organic synthesis pathways.
| Molecular weight | 387.43 |
|---|---|
| Empirical formula | C24H21NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-D-Phe-OH used for?
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Fmoc-β-D-Phe-OH is primarily used as a building block in peptide synthesis, chemical biology research, and drug discovery to create peptides and peptidomimetics containing unnatural beta-amino acids.
What are the CAS number and formula for Fmoc-β-D-Phe-OH?
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The CAS number for Fmoc-β-D-Phe-OH is 209252-15-3, and its empirical formula is C24H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-D-Phe-OH with a purity of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-β-D-Phe-OH be handled and stored?
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Handle Fmoc-β-D-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter may be necessary. Store the product at 2-8°C.
Is Fmoc-β-D-Phe-OH a hazardous substance?
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According to WGK Germany, this substance is rated 3, indicating it is hazardous. It is essential to follow safety precautions during handling and storage.
How is Fmoc-β-D-Phe-OH packed and exported?
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Tech Serve Solutions securely packs and exports Fmoc-β-D-Phe-OH according to international shipping regulations for chemical products.
How can I request a sample or quote for Fmoc-β-D-Phe-OH?
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To request a sample or quote for Fmoc-β-D-Phe-OH, please contact our sales team through the website or by phone.
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