Fmoc-β-Ala-OH
Fmoc-β-Ala-OH (CAS 35737-10-1) is a derivative of beta-alanine, featuring the fluorenylmethyloxycarbonyl (Fmoc) protecting group. With a molecular formula of C18H17NO4 and a molecular weight of 311.33 g/mol, it is a key building block in peptide synthesis. Its primary applications lie in the construction of unnatural peptides and modified biomolecules, offering enhanced stability or specific functionalities.
- IUPAC
- Fmoc-β-alanine
Peptide Synthesis
Fmoc-β-Ala-OH is utilized as a protected unnatural amino acid in solid-phase peptide synthesis (SPPS) and solution-phase synthesis. It allows for the incorporation of beta-alanine residues into peptide sequences, enabling the creation of peptides with altered conformational properties or improved resistance to enzymatic degradation.
Chemical Biology Research
This compound serves as a valuable tool in chemical biology for creating modified peptides and peptidomimetics. These molecules can be employed to probe biological pathways, develop diagnostic agents, or explore protein-protein interactions with greater precision.
Drug Discovery and Development
In pharmaceutical research, Fmoc-β-Ala-OH aids in the synthesis of novel therapeutic peptides and drug conjugates. The introduction of beta-alanine can modify pharmacokinetic properties, such as bioavailability and half-life, which are critical for drug efficacy.
Materials Science
The incorporation of Fmoc-β-Ala-OH into polymeric structures or self-assembling systems can lead to novel biomaterials. These materials may find applications in areas like tissue engineering or targeted drug delivery systems.
| Molecular weight | 311.33 |
|---|---|
| Empirical formula | C18H17NO4 |
| Assay | ≥99.0% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 142-147 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Ala-OH used for?
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Fmoc-β-Ala-OH is primarily used as a protected building block in peptide synthesis, enabling the incorporation of beta-alanine into peptide chains. It is also employed in chemical biology and drug discovery for creating modified peptides and peptidomimetics with altered properties.
What are the CAS number and molecular formula for Fmoc-β-Ala-OH?
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The CAS number for Fmoc-β-Ala-OH is 35737-10-1, and its molecular formula is C18H17NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Ala-OH?
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Tech Serve Solutions supplies Fmoc-β-Ala-OH with a purity of ≥99.0% determined by HPLC. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-β-Ala-OH be handled and stored?
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Fmoc-β-Ala-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. It should be stored at refrigeration temperatures between 2-8°C.
Is Fmoc-β-Ala-OH a controlled substance?
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Based on the provided data, Fmoc-β-Ala-OH is not indicated as a controlled substance.
How are Tech Serve Solutions' chemicals packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to stringent quality and safety standards for all packaging and export processes.
How can I request a quote or sample for Fmoc-β-Ala-OH?
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To request a quote or sample for Fmoc-β-Ala-OH, please visit the Tech Serve Solutions website or contact our sales department directly through the provided contact channels.
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