Fmoc-β-Gln-OH
Fmoc-β-Gln-OH (CAS: 283160-18-9) is a chemical compound with the formula C20H20N2O5 and a molecular weight of 368.38 g/mol. It is an unnatural amino acid derivative, primarily used in peptide chemistry for the synthesis of modified peptides and peptidomimetics. Its structure allows for the incorporation of beta-amino acid residues into peptide chains, expanding the possibilities in drug discovery and biochemical research.
- IUPAC
- (S)-3-(Fmoc-amino)pentanoic acid 5-amide,Nβ-Fmoc-L-β-glutamine,Nβ-Fmoc-L-β-homoasparagine
Peptide Synthesis
Fmoc-β-Gln-OH serves as a protected building block in solid-phase and solution-phase peptide synthesis. It enables the introduction of unnatural beta-glutamine residues, facilitating the creation of peptides with novel structures and properties.
Chemical Biology
This compound is valuable in chemical biology for creating peptides with altered conformational stability or biological activity. It can be used to probe structure-activity relationships and develop peptide-based therapeutics.
Drug Discovery
As an unnatural amino acid derivative, Fmoc-β-Gln-OH is employed in the design and synthesis of peptidomimetics and novel drug candidates. Its unique structure can confer improved pharmacokinetic properties or receptor binding.
Chemical Synthesis
It acts as a versatile reagent in organic synthesis, particularly for the construction of complex molecules containing beta-amino acid motifs. The Fmoc protecting group facilitates controlled deprotection and subsequent coupling reactions.
| Molecular weight | 368.38 |
|---|---|
| Empirical formula | C20H20N2O5 |
| Assay | ≥97.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Gln-OH used for?
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Fmoc-β-Gln-OH is used in peptide synthesis to incorporate unnatural beta-glutamine residues, in chemical biology for creating modified peptides, and in drug discovery for developing novel therapeutics and peptidomimetics.
What is the CAS number and molecular formula for Fmoc-β-Gln-OH?
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The CAS number is 283160-18-9 and the molecular formula is C20H20N2O5.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Gln-OH?
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Tech Serve Solutions supplies Fmoc-β-Gln-OH with an assay of ≥97.0%. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-β-Gln-OH be handled and stored?
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Handle Fmoc-β-Gln-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-β-Gln-OH classified as hazardous?
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Yes, Fmoc-β-Gln-OH has a WGK (Germany) classification of 3, indicating it is hazardous.
How is Fmoc-β-Gln-OH packed and shipped?
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Fmoc-β-Gln-OH is carefully packed according to industry standards for chemical export and can be shipped globally by Tech Serve Solutions.
How can I request a sample or quote for Fmoc-β-Gln-OH?
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Please contact the Tech Serve Solutions sales team via our website or direct email to request a sample or obtain a quotation for Fmoc-β-Gln-OH.
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