Fmoc-β-(3-thienyl)-D-Ala-OH
Fmoc-β-(3-thienyl)-D-Ala-OH (CAS: 220497-90-5), with the molecular formula C22H19NO4S and a molecular weight of 393.46 g/mol, is a protected unnatural amino acid derivative. It is a valuable building block utilised in peptide chemistry and chemical synthesis. This compound finds application in research settings, particularly for incorporating non-canonical amino acids into peptide sequences, which can lead to novel pharmacological or biochemical properties.
- IUPAC
- Fmoc-3-(3-thienyl)-D-alanine
- Synonyms
- Fmoc-3-(3-thienyl)-D-alanine
Peptide Synthesis
Serves as a specialised building block for the synthesis of peptides containing unnatural amino acid residues. Its structure allows for the introduction of a thienyl moiety into peptide chains, modifying their biological activity or structural characteristics.
Chemical Biology Research
Enables the creation of modified peptides for investigating protein-ligand interactions or developing novel peptide-based therapeutics. The thienyl group can influence binding affinity or provide a unique spectroscopic handle.
Drug Discovery
Facilitates the development of new chemical entities by allowing medicinal chemists to explore diverse structural motifs in peptide drug candidates. This can lead to improved pharmacokinetic profiles or enhanced target engagement.
Organic Synthesis
Acts as a chiral synthon in complex organic synthesis pathways. The Fmoc protecting group facilitates controlled coupling reactions, typical in solid-phase or solution-phase peptide synthesis.
| Molecular weight | 393.46 |
|---|---|
| Empirical formula | C22H19NO4S |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(3-thienyl)-D-Ala-OH used for?
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Fmoc-β-(3-thienyl)-D-Ala-OH is primarily used as a specialised building block in peptide synthesis and chemical biology research, particularly for creating peptides with unnatural amino acid residues and exploring novel drug discovery pathways.
What are the CAS number and formula for Fmoc-β-(3-thienyl)-D-Ala-OH?
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The CAS number is 220497-90-5 and the empirical formula is C22H19NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(3-thienyl)-D-Ala-OH with an assay of ≥98.0%. This is a research-grade material, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should Fmoc-β-(3-thienyl)-D-Ala-OH be handled?
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Handle Fmoc-β-(3-thienyl)-D-Ala-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is this product typically shipped and exported?
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Fmoc-β-(3-thienyl)-D-Ala-OH is typically stored at 2-8°C and carefully packaged for domestic and international export by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or obtain a quote for Fmoc-β-(3-thienyl)-D-Ala-OH?
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To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (220497-90-5).
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