2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane
2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CAS: 14812-59-0; C6H12ClO2P; MW: 182.59) is a phosphorus precursor used in chemical synthesis. This compound serves as a valuable reagent for the phosphitylation of alcohols and heteroatomic nucleophiles. It is instrumental in the formation of glycosyl donors and ligands, finding applications within catalysis and inorganic chemistry. Tech Serve Solutions supplies this chemical with an assay of 95%.
- Synonyms
- 5-tetramethyl-1,3,2-dioxaphospholane14812-59-0C6H12ClO2P
Phosphitylation Reagent
Utilised for the phosphitylation of alcohols and heteroatomic nucleophiles. This reaction is key in the synthesis of complex organic molecules.
Glycosyl Donor Formation
Enables the formation of useful glycosyl donors. These are important intermediates in carbohydrate chemistry and related fields.
Ligand Synthesis
Acts as a precursor for the synthesis of specialised ligands. These ligands can be employed in various catalytic applications.
Catalysis and Inorganic Chemistry
Its properties make it suitable for applications in catalysis and broader inorganic chemistry research and development.
| Molecular weight | 182.59 |
|---|---|
| Empirical formula | C6H12ClO2P |
| Assay | 95% |
| Boiling point | 81.5-82 °C/13 mmHg(lit.) |
| Density | 1.149 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.471(lit.) |
| Application | Reagent used for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 22-26-27-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane used for?
+
This compound is used as a reagent for the phosphitylation of alcohols and heteroatomic nucleophiles, facilitating the formation of glycosyl donors and ligands in chemical synthesis.
What are the CAS number and chemical formula for this product?
+
The CAS number is 14812-59-0, and the empirical formula (Hill notation) is C6H12ClO2P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 95%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane be handled safely?
+
This compound is corrosive and reacts violently with water. Handle with extreme care, using appropriate personal protective equipment including a faceshield, gloves, goggles, and a suitable respirator. Ensure adequate ventilation and avoid contact with water.
Is this chemical suitable for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents. Please contact us for export details and capabilities.
How can I request a sample or quote?
+
To request a sample or a quote for 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, please use the contact form or contact details provided on the Tech Serve Solutions website.
▶ Related products
Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis