5,5-Dimethyl-1-pyrroline N-oxide
5,5-Dimethyl-1-pyrroline N-oxide (CAS 3317-61-1), a heterocyclic compound with the molecular formula C6H11NO, is primarily utilized as a neuroprotective agent and a nitric oxide spin trap. Its ability to study radicals formed during enzymatic acetaldehyde oxidation makes it valuable in biochemical research. It is also noted for its role in reducing DNA damage induced by nickel chloride in lymphocytes.
- IUPAC
- DMPO
- Synonyms
- DMPO
Nitric Oxide Spin Trapping
This compound serves as an effective spin trap for nitric oxide, enabling researchers to detect and study transient radical species in biological systems. Its application aids in understanding the complex roles of NO in physiological and pathological processes.
Neuroprotection Studies
5,5-Dimethyl-1-pyrroline N-oxide exhibits neuroprotective properties, making it a valuable tool for investigating mechanisms of neuronal damage and potential therapeutic interventions. Its use in research contributes to the understanding of neurological disorders.
Radical Detection in Enzymatic Reactions
It is employed to investigate free radicals generated during enzymatic oxidation of acetaldehyde. This application is crucial for elucidating reaction pathways and the role of specific enzymes in metabolic processes.
Cellular Damage Research
Research has shown that incubation with 5,5-Dimethyl-1-pyrroline N-oxide can mitigate DNA damage in lymphocytes caused by nickel chloride exposure. This highlights its potential in studying and protecting against oxidative stress in cellular environments.
| Molecular weight | 113.16 |
|---|---|
| Empirical formula | C6H11NO |
| Assay | 97% |
| Boiling point | 75 °C/0.4 mmHg(lit.) |
| Density | 1.015 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.496(lit.) |
| Storage temperature | −20°C |
| Melting point | 25-29 °C(lit.) |
| Application | Neuroprotective agent; nitric oxide spin trap. Used to study radicals formed by enzymatic acetaldehyde oxidation. Incubation of lymphocytes with DMPO decreased DNA damage by NiCl2. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 95 °C / 203 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5,5-Dimethyl-1-pyrroline N-oxide used for?
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5,5-Dimethyl-1-pyrroline N-oxide is used as a neuroprotective agent and a nitric oxide spin trap. It is also employed to study radicals formed by enzymatic acetaldehyde oxidation and to reduce DNA damage in lymphocytes.
What is the CAS number and molecular formula for 5,5-Dimethyl-1-pyrroline N-oxide?
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The CAS number for 5,5-Dimethyl-1-pyrroline N-oxide is 3317-61-1 and its molecular formula is C6H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5,5-Dimethyl-1-pyrroline N-oxide with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for 5,5-Dimethyl-1-pyrroline N-oxide?
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Safety precautions include wearing eyeshields, gloves, and appropriate respiratory protection such as a half-mask respirator or multi-purpose combination respirator cartridge. The compound has a flash point of 95 °C (203 °F) and requires storage at -20°C. Consult the Safety Data Sheet for detailed handling information.
How is 5,5-Dimethyl-1-pyrroline N-oxide packed and shipped?
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5,5-Dimethyl-1-pyrroline N-oxide is carefully packed and exported by Tech Serve Solutions, adhering to all relevant transportation regulations for chemical compounds.
How can I request a sample or quote for 5,5-Dimethyl-1-pyrroline N-oxide?
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To request a sample or quote for 5,5-Dimethyl-1-pyrroline N-oxide, please contact our sales department through the website or by phone, providing your specific requirements.
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