5,5,5-Trifluoro-DL-leucine
5,5,5-Trifluoro-DL-leucine (CAS: 2792-72-5) is a trifluoromethylated analogue of the essential amino acid leucine. With the empirical formula C6H10F3NO2 and a molecular weight of 185.14 g/mol, this compound serves as a valuable building block in chemical synthesis and research. It is particularly useful in areas such as chemical biology and peptide chemistry for introducing fluorinated moieties into molecules, potentially altering their properties and biological activity.
- IUPAC
- (±)-2-Amino-4-(trifluoromethyl)pentanoic acid
- Synonyms
- 2792-72-5C6H10F3NO2(±)-2-Amino-4-(trifluoromethyl)pentanoic acid
Chemical Synthesis
5,5,5-Trifluoro-DL-leucine is employed as a specialised reagent in organic synthesis. Its unique trifluoromethyl group allows for the creation of novel fluorinated organic compounds with tailored characteristics.
Peptide Chemistry
This unnatural amino acid derivative can be incorporated into peptide chains. The presence of the trifluoromethyl group can influence peptide conformation, stability, and binding interactions.
Chemical Biology Research
Researchers utilise 5,5,5-Trifluoro-DL-leucine to investigate structure-activity relationships and develop new biochemical probes. The fluorine atom can serve as a useful NMR marker.
Development of Novel Materials
The compound's structure makes it suitable for research into new fluorinated materials. Incorporation into polymers or other complex molecules could impart unique physical or chemical properties.
| Molecular weight | 185.14 |
|---|---|
| Empirical formula | C6H10F3NO2 |
| Assay | ≥98.0% (sum of isomers, HPLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5,5,5-Trifluoro-DL-leucine used for?
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5,5,5-Trifluoro-DL-leucine is used in chemical synthesis, peptide chemistry, and chemical biology research. It serves as a fluorinated building block for creating novel compounds and investigating structure-activity relationships.
What is the CAS number and formula for 5,5,5-Trifluoro-DL-leucine?
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The CAS number is 2792-72-5, and the empirical formula is C6H10F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5,5,5-Trifluoro-DL-leucine with an assay of ≥98.0% (sum of isomers, HPLC). This product is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 5,5,5-Trifluoro-DL-leucine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is 5,5,5-Trifluoro-DL-leucine classified as a hazardous substance?
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Yes, 5,5,5-Trifluoro-DL-leucine is classified as a Warning substance (GHS07). It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
Does Tech Serve Solutions export 5,5,5-Trifluoro-DL-leucine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5,5,5-Trifluoro-DL-leucine.
How can I request a sample or quote for 5,5,5-Trifluoro-DL-leucine?
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Please contact our sales team through our website or by telephone to request a sample or a quotation for 5,5,5-Trifluoro-DL-leucine.
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