2,5-Dimethoxytetrahydrofuran
2,5-Dimethoxytetrahydrofuran (CAS: 696-59-3), with the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol, is a heterocyclic organic compound. This furan derivative serves as a versatile building block in chemical synthesis. It is often employed in the preparation of more complex organic molecules and pharmaceutical intermediates due to its reactive functionalities. Available at a purity of ≥97.0% (GC), it is suitable for a wide range of laboratory and industrial applications.
- Synonyms
- Tetrahydrofuran, 2,5-dimethoxy-

Chemical Synthesis
2,5-Dimethoxytetrahydrofuran is a valuable intermediate in organic synthesis. Its structure allows for various chemical transformations, making it useful in the construction of more complex molecules.
Pharmaceutical Intermediates
This compound can be utilised in the synthesis pathways for pharmaceutical ingredients. Its furan ring and methoxy groups offer specific reactivity for developing novel drug candidates.
Heterocyclic Chemistry
As a furan derivative, it is an important building block in heterocyclic chemistry. It facilitates the introduction of furan moieties into larger molecular structures.
| Molecular weight | 132.16 |
|---|---|
| Empirical formula | C6H12O3 |
| Assay | ≥97.0% (GC) |
| Boiling point | 143-146 °C(lit.) |
| Density | 1.023 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.418 |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 38 °C / 100.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dimethoxytetrahydrofuran used for?
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2,5-Dimethoxytetrahydrofuran is primarily used as a building block in chemical synthesis, particularly for creating pharmaceutical intermediates and other complex organic molecules. It is a valuable component in heterocyclic chemistry.
What is the CAS number and formula for 2,5-Dimethoxytetrahydrofuran?
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The CAS number for 2,5-Dimethoxytetrahydrofuran is 696-59-3, and its empirical formula (Hill Notation) is C6H12O3.
What grade and purity does Tech Serve Solutions supply for 2,5-Dimethoxytetrahydrofuran?
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Tech Serve Solutions supplies 2,5-Dimethoxytetrahydrofuran with a purity of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated in the product documentation.
How should 2,5-Dimethoxytetrahydrofuran be handled and stored safely?
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2,5-Dimethoxytetrahydrofuran is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and chemical-resistant gloves, and ensure adequate ventilation when handling. Store in a well-ventilated area away from ignition sources.
How is 2,5-Dimethoxytetrahydrofuran packed and exported?
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2,5-Dimethoxytetrahydrofuran is carefully packed according to international shipping regulations for hazardous materials, including UN 1993 classification (C3, PGIII). As a global supplier and exporter, Tech Serve Solutions ensures compliant and secure packaging for international shipment.
How can I request a sample or quote for 2,5-Dimethoxytetrahydrofuran?
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To request a sample or a quote for 2,5-Dimethoxytetrahydrofuran, please contact our sales department via the website or by phone. Provide your specific requirements, and we will respond promptly.
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