5,5-Dimethylhydantoin
5,5-Dimethylhydantoin (CAS 77-71-4), also known as C5H8N2O2, is a versatile heterocyclic organic compound with a molecular weight of 128.13 g/mol. It serves as a key reactant in various chemical syntheses, including the development of novel antimicrobials, biocidal materials, and inhibitors for viral and bacterial targets. Its chemical structure makes it a valuable building block in advanced organic chemistry.
- IUPAC
- 4,4-Dimethyl-2,5-dioxoimidazolidine,DMH,Fennosurf 300
- Synonyms
- 4,4-Dimethyl-2,5-dioxoimidazolidine, DMH, Fennosurf 300

Antimicrobial Synthesis
5,5-Dimethylhydantoin is utilised as a reactant in the synthesis of N-chloroheterocyclic antimicrobials. This application highlights its role in developing new agents for combating microbial infections.
Inhibitor Development
This compound is a precursor for synthesising β-amino alcohols, which act as inhibitors of N-acetyltransferase, a target relevant to antitubercular therapies. It also features in the development of selective inhibitors for the hepatitis C virus NS3 serine protease.
Biocidal Materials
5,5-Dimethylhydantoin is employed in the creation of rechargeable biocidal cellulose, indicating its utility in developing materials with self-sanitizing properties for various applications.
Chlorolactonization Reactions
The compound serves as a reactant in asymmetric chlorolactonization reactions, a specialised synthetic methodology in organic chemistry.
| Molecular weight | 128.13 |
|---|---|
| Empirical formula | C5H8N2O2 |
| Assay | 97% |
| Application | Reactant for synthesis of:• N-chloroheterocyclic antimicrobials1• β-Amino alcohols as inhibitors of antitubercular target N-acetyltransferase2• Second-generation selective inhibitors of hepatitis C virus NS3 serine protease3• Rechargeable biocidal cellulose4• N-chlorohydantoins5Reactant for asymmetric chlorolactonization reactions6 |
| Melting point | 174-177 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5,5-Dimethylhydantoin used for?
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5,5-Dimethylhydantoin is used as a reactant in the synthesis of N-chloroheterocyclic antimicrobials, β-amino alcohols as inhibitors of antitubercular targets, second-generation selective inhibitors of hepatitis C virus NS3 serine protease, rechargeable biocidal cellulose, and N-chlorohydantoins. It is also used in asymmetric chlorolactonization reactions.
What is the CAS number and formula for 5,5-Dimethylhydantoin?
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The CAS number for 5,5-Dimethylhydantoin is 77-71-4, and its empirical formula is C5H8N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5,5-Dimethylhydantoin with an assay of 97%. This product is not supplied as USP, BP, or EP grade and is intended for research and chemical synthesis purposes.
How should 5,5-Dimethylhydantoin be handled safely?
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Safe handling of 5,5-Dimethylhydantoin requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling guidelines.
Is 5,5-Dimethylhydantoin a controlled substance?
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Based on the provided data, 5,5-Dimethylhydantoin is not indicated as a controlled substance.
How is 5,5-Dimethylhydantoin packaged and exported?
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5,5-Dimethylhydantoin is available from Tech Serve Solutions and is packaged according to industry standards for safe transport and export globally.
How can I request a quote or sample for 5,5-Dimethylhydantoin?
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To request a quote or a sample of 5,5-Dimethylhydantoin, please contact our sales team through the website or designated contact channels.
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