Fmoc-β-(2-thienyl)-Ala-OH
Fmoc-β-(2-thienyl)-Ala-OH (CAS: 130309-35-2), a protected unnatural amino acid derivative with the empirical formula C22H19NO4S and a molecular weight of 393.46 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its unique structure, featuring a thienyl side chain, allows for the incorporation of novel properties into peptides and other biomolecules.
- IUPAC
- (S)-2-(Fmoc-amino)-3-(2-thienyl)propionic acid,Fmoc-3-(2-thienyl)-L-alanine

Peptide Synthesis
Fmoc-β-(2-thienyl)-Ala-OH is employed in solid-phase and solution-phase peptide synthesis to introduce a thienylalanine residue. This enables the creation of peptides with modified structures for research into biological activity and drug discovery.
Chemical Biology Research
The compound is utilised in chemical biology to synthesise peptides and peptidomimetics with unique functionalities. These molecules can be used to probe biological pathways, develop diagnostic tools, or investigate protein interactions.
Organic Synthesis
As an unnatural amino acid derivative, it finds application in broader organic synthesis projects requiring the specific incorporation of the thienylalanine moiety into complex molecular architectures.
| Molecular weight | 393.46 |
|---|---|
| Empirical formula | C22H19NO4S |
| Assay | ≥98.0% |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(2-thienyl)-Ala-OH used for?
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Fmoc-β-(2-thienyl)-Ala-OH is primarily used as a building block in peptide synthesis and chemical biology research for the incorporation of unnatural amino acid residues into peptides and other biomolecules.
What is the CAS number and formula for Fmoc-β-(2-thienyl)-Ala-OH?
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The CAS number is 130309-35-2 and the empirical formula is C22H19NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-(2-thienyl)-Ala-OH with an assay of ≥98.0%. This product is intended for research and development purposes; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling Fmoc-β-(2-thienyl)-Ala-OH?
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This compound is classified with hazard statement H413 (May cause long lasting harmful effects to aquatic life). Appropriate personal protective equipment, including eyeshields, gloves, and an appropriate respirator filter (type N95 or P1), should be used during handling.
How is Fmoc-β-(2-thienyl)-Ala-OH packed, shipped, and exported?
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Fmoc-β-(2-thienyl)-Ala-OH is carefully packaged to ensure stability during transit and is available for global export by Tech Serve Solutions, a trusted supplier since 1998.
How can I request a sample or quote for Fmoc-β-(2-thienyl)-Ala-OH?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via the website or direct email, providing your specific requirements and shipping details.
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