Fmoc-β-(2-pyridyl)-Ala-OH
Fmoc-β-(2-pyridyl)-Ala-OH (CAS: 185379-40-2) is a protected unnatural amino acid derivative with the empirical formula C23H20N2O4 and a molecular weight of 388.42 g/mol. This compound is a valuable building block in chemical synthesis, particularly in peptide chemistry and chemical biology. Its structure facilitates the incorporation of a pyridyl-alanine residue into peptides, enabling the development of novel biomolecules and research tools.
- IUPAC
- Fmoc-3-(2-pyridyl)-L-alanine

Peptide Synthesis
Fmoc-β-(2-pyridyl)-Ala-OH serves as a key intermediate in solid-phase and solution-phase peptide synthesis. Its Fmoc protecting group allows for orthogonal deprotection strategies, crucial for building complex peptide sequences with unnatural amino acids.
Chemical Biology Research
This unnatural amino acid derivative is utilised in chemical biology to create peptides with unique structural or functional properties. The incorporated pyridyl group can participate in metal coordination or influence molecular interactions.
Medicinal Chemistry
It is employed in medicinal chemistry for the design and synthesis of novel therapeutic agents. Incorporating unnatural amino acids can enhance peptide stability, bioavailability, and target binding affinity.
Materials Science
The unique properties of pyridyl-alanine residues can be exploited in the development of new peptide-based materials with specific electronic or binding characteristics.
| Molecular weight | 388.42 |
|---|---|
| Empirical formula | C23H20N2O4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-(2-pyridyl)-Ala-OH used for?
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Fmoc-β-(2-pyridyl)-Ala-OH is primarily used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, medicinal chemistry, and materials science.
What is the CAS number and molecular formula for Fmoc-β-(2-pyridyl)-Ala-OH?
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The CAS number is 185379-40-2, and the molecular formula is C23H20N2O4.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-(2-pyridyl)-Ala-OH?
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Tech Serve Solutions supplies Fmoc-β-(2-pyridyl)-Ala-OH with an assay of ≥97.0% (HPLC). This product is typically considered research grade, and TSS does not represent it as USP, BP, or EP grade.
How should Fmoc-β-(2-pyridyl)-Ala-OH be handled and stored?
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Handle Fmoc-β-(2-pyridyl)-Ala-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter may be necessary. It should be stored at 2-8°C. The compound is classified under WGK Germany 3.
Is Fmoc-β-(2-pyridyl)-Ala-OH a controlled substance?
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Based on the provided data, there is no indication that Fmoc-β-(2-pyridyl)-Ala-OH is a controlled substance.
How is Fmoc-β-(2-pyridyl)-Ala-OH packed, shipped, and exported?
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Fmoc-β-(2-pyridyl)-Ala-OH is carefully packed to ensure stability during transit. Tech Serve Solutions is a global supplier and exporter, experienced in handling and shipping fine chemicals worldwide.
How can I request a sample or quote for Fmoc-β-(2-pyridyl)-Ala-OH?
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To request a sample or quote for Fmoc-β-(2-pyridyl)-Ala-OH, please contact our sales team through the website or direct inquiry channels.
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