(R)-(−)-Pyrrolidine-3-carboxylic acid
(R)-(−)-Pyrrolidine-3-carboxylic acid (CAS: 72580-54-2), with the molecular formula C5H9NO2 and a molecular weight of 115.13 g/mol, is a chiral building block. This unnatural amino acid derivative, also known as (R)-β-Proline, is valuable in asymmetric synthesis and peptide chemistry. Its specific optical activity and defined structure make it a key intermediate for developing complex molecules and specialised reagents in research and development settings.
- IUPAC
- (R)-β-Proline
- Synonyms
- (R)-β-Proline
Asymmetric Synthesis
Serves as a chiral building block for synthesising enantiomerically pure compounds. It is particularly useful in the development of new chiral catalysts and ligands.
Peptide Chemistry
Incorporated into peptide chains as an unnatural amino acid to modify structure and function. This allows for the creation of novel peptides with enhanced stability or unique biological activities.
Organocatalysis
Functions as a precursor for proline-based organocatalysts. These catalysts are employed in various enantioselective transformations within organic synthesis.
Chemical Biology and Drug Discovery
Used in the synthesis of complex heterocyclic compounds and as a component in the development of new pharmaceutical intermediates. Its chiral nature is essential for stereospecific drug design.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]/D -20.5±1.5°, c = 2 in H2O |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-Pyrrolidine-3-carboxylic acid used for?
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(R)-(−)-Pyrrolidine-3-carboxylic acid is primarily used as a chiral building block in asymmetric synthesis, peptide chemistry, and the development of organocatalysts. It is also valuable in chemical biology and pharmaceutical intermediate synthesis.
What are the CAS number and formula for (R)-(−)-Pyrrolidine-3-carboxylic acid?
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The CAS number is 72580-54-2, and the molecular formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-Pyrrolidine-3-carboxylic acid with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this chemical?
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This chemical requires the use of eyeshields and gloves, along with a type N95 (US) or type P1 (EN143) respirator filter. It is classified with WGK Germany 3, indicating a high hazard to water.
How is this chemical shipped and exported?
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This chemical is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant packaging and documentation for international shipment.
How can I request a quote or sample?
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To request a quote or sample of (R)-(−)-Pyrrolidine-3-carboxylic acid, please contact our sales team through the website or by phone, providing your specific requirements.
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