(R)-(−)-sec-Butylamine
(R)-(−)-sec-Butylamine (CAS: 13250-12-9), a chiral amine with the formula C2H5CH(NH2)CH3, has a molecular weight of 73.14 g/mol. This optically active compound serves as a valuable chiral building block in organic synthesis. It is frequently employed in asymmetric synthesis and as a key intermediate in the preparation of more complex organic molecules, finding utility across various chemical research and development sectors.
- IUPAC
- (R)-(−)-2-Aminobutane

Chiral Building Block
As an enantiomerically enriched compound, (R)-(−)-sec-Butylamine is crucial for constructing chiral molecules. Its defined stereochemistry allows for precise control in the synthesis of complex target molecules, particularly in pharmaceutical research.
Asymmetric Synthesis
This amine is widely utilized as a chiral auxiliary or resolving agent in asymmetric synthesis. It facilitates the stereoselective formation of new chiral centres, enabling the production of single enantiomer products.
Organic Synthesis Intermediate
It serves as a versatile intermediate in the synthesis of diverse organic compounds. Its amine functionality allows for various chemical transformations, making it a useful starting material for fine chemical production.
| Molecular weight | 73.14 |
|---|---|
| Linear formula | C2H5CH(NH2)CH3 |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Boiling point | 63 °C(lit.) |
| Density | 0.72 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.393(lit.)n20/D 1.393 |
| Optical activity | [α]20/D −8.0±0.5°, neat |
| Optical purity | enantiomeric ratio: ≥97.0:3.0 (GC) |




Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H400Very toxic to aquatic life
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -19 °C / -2.2 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-20/22-35-50 |
| Safety statements (S) | 9-16-26-28-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-sec-Butylamine used for?
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(R)-(−)-sec-Butylamine is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic synthesis. Its defined stereochemistry is essential for constructing complex chiral molecules.
What are the CAS number and formula for (R)-(−)-sec-Butylamine?
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The CAS number for (R)-(−)-sec-Butylamine is 13250-12-9, and its linear formula is C2H5CH(NH2)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-sec-Butylamine with an assay of ≥99.0% (sum of enantiomers, GC). This product is not represented as USP, BP, or EP grade.
How is (R)-(−)-sec-Butylamine safely handled?
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(R)-(−)-sec-Butylamine is a flammable liquid and vapour (H225), harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and harmful if inhaled (H332). It is also very toxic to aquatic life (H400). Strict adherence to safety protocols, including the use of appropriate personal protective equipment such as gloves, goggles, and a respirator, is essential.
Does TSS export (R)-(−)-sec-Butylamine?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(−)-sec-Butylamine.
How can I request a sample or quote for (R)-(−)-sec-Butylamine?
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To request a sample or quote for (R)-(−)-sec-Butylamine, please use the contact form on our website or call our sales department.
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