(R)-(−)-α-(Trifluoromethyl)benzyl alcohol
(R)-(−)-α-(Trifluoromethyl)benzyl alcohol (CAS: 10531-50-7, Formula: C6H5CH(CF3)OH, Molar Mass: 176.14) is a chiral organic compound. This fluorinated alcohol serves as a valuable building block in asymmetric synthesis and chemical research. Its unique trifluoromethyl group imparts specific properties, making it useful in the development of novel pharmaceutical intermediates and advanced materials. Tech Serve Solutions supplies this high-purity reagent for demanding synthetic applications.
- IUPAC
- (−)-Phenyl(trifluoromethyl)carbinol,(R)-(−)-1-Phenyl-2,2,2-trifluoroethanol
- Synonyms
- (R)-1-Phenyl-2,2,2-trifluoroethanol
Chiral Building Block
This enantiomerically enriched alcohol is essential for constructing complex chiral molecules. It is frequently employed in the stereoselective synthesis of pharmaceutical active ingredients and other fine chemicals where specific stereochemistry is critical.
Asymmetric Synthesis
Utilised as a chiral auxiliary or precursor, (R)-(−)-α-(Trifluoromethyl)benzyl alcohol plays a key role in asymmetric transformations. Its incorporation allows for the creation of specific enantiomers with high optical purity.
Derivatization Reagent
This compound can be used as a derivatizing agent in analytical chemistry, particularly for HPLC. It reacts with other molecules to form derivatives that are more easily detected or separated chromatographically.
Organic Synthesis Intermediate
As a fluorinated organic building block, it is a versatile intermediate for introducing the trifluoromethyl group and a chiral centre into larger molecules. This is valuable in medicinal chemistry and materials science.
| Molecular weight | 176.14 |
|---|---|
| Linear formula | C6H5CH(CF3)OH |
| Assay | 99% |
| Grade | puriss. |
| Boiling point | 73-76 °C/9 mmHg(lit.) |
| Density | 1.300 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.459(lit.) |
| Melting point | 20 °C(lit.) |
| Optical activity | [α]21/D −29°, c = 2.6 in chloroform |
| Optical purity | ee: 97% (GLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-α-(Trifluoromethyl)benzyl alcohol used for?
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It is primarily used as a chiral building block in asymmetric synthesis, for creating chiral molecules, and as a derivatization reagent in analytical chemistry.
What is the CAS number and formula for (R)-(−)-α-(Trifluoromethyl)benzyl alcohol?
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The CAS number is 10531-50-7 and the molecular formula is C6H5CH(CF3)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a purity of 99% (puriss. grade). We do not represent this product as USP, BP, or EP grade.
How should (R)-(−)-α-(Trifluoromethyl)benzyl alcohol be handled?
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This compound is a warning hazardous substance (H315, H319, H335) causing skin, eye, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area.
How is (R)-(−)-α-(Trifluoromethyl)benzyl alcohol packed and shipped?
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Products are carefully packed and exported by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quote or a sample of (R)-(−)-α-(Trifluoromethyl)benzyl alcohol.
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