(R)-(−)-α-Methoxyphenylacetic acid
(R)-(−)-α-Methoxyphenylacetic acid (CAS: 3966-32-3), with the chemical formula C6H5CH(OCH3)CO2H and a molecular weight of 166.17 g/mol, is a chiral carboxylic acid. It serves as a valuable chiral building block and resolving agent in asymmetric synthesis. This compound is essential for researchers and manufacturers involved in creating stereochemically pure substances, particularly in the pharmaceutical and fine chemical industries, enabling precise control over molecular chirality.
- IUPAC
- O-Methyl-D-mandelic acid
- Synonyms
- O-Methyl-D-mandelic acid
Chiral Resolving Agent
Utilised in the separation of racemic mixtures into individual enantiomers, facilitating the isolation of specific stereoisomers crucial for pharmaceutical development.
Chiral Building Block
Serves as a fundamental component in the stereoselective synthesis of complex chiral molecules, offering a defined stereogenic centre.
Asymmetric Synthesis
Employed as a precursor or auxiliary in reactions designed to produce chiral compounds with high enantiomeric purity.
Organic Synthesis Intermediate
Acts as a versatile intermediate in the multi-step synthesis of various organic compounds, including active pharmaceutical ingredients.
| Molecular weight | 166.17 |
|---|---|
| Linear formula | C6H5CH(OCH3)CO2H |
| Assay | 99% |
| Optical activity | [α]20/D −146°, c = 0.5 in ethanol |
| Melting point | 66-68 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-α-Methoxyphenylacetic acid used for?
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(R)-(−)-α-Methoxyphenylacetic acid is primarily used as a chiral resolving agent and a chiral building block in asymmetric synthesis, particularly in the development of stereochemically pure compounds for the pharmaceutical and fine chemical industries.
What is the CAS number and chemical formula for (R)-(−)-α-Methoxyphenylacetic acid?
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The CAS number is 3966-32-3 and the chemical formula is C6H5CH(OCH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-α-Methoxyphenylacetic acid with an assay of 99%. This product is suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
How should (R)-(−)-α-Methoxyphenylacetic acid be handled?
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Handle with care. This compound is a skin, eye, and respiratory irritant (H315, H319, H335). Use a dust mask (N95 US standard), eyeshields, and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling instructions.
Is (R)-(−)-α-Methoxyphenylacetic acid a controlled substance?
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The provided data does not indicate that (R)-(−)-α-Methoxyphenylacetic acid is a controlled substance.
How is (R)-(−)-α-Methoxyphenylacetic acid packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote for (R)-(−)-α-Methoxyphenylacetic acid?
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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number (3966-32-3).
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