(R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone
(R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone (CAS: 33019-03-3), a chiral building block with the molecular formula C7H10O4 and a molecular weight of 158.15 g/mol, is a valuable intermediate in asymmetric synthesis. This lactone derivative is primarily employed in organic synthesis for the construction of complex chiral molecules. Its specific stereochemistry makes it a sought-after reagent for stereoselective reactions in pharmaceutical and fine chemical research.
- IUPAC
- Ethyl (R)-(−)-5-oxotetrahydro-2-furancarboxylate

Asymmetric Synthesis
Serves as a chiral building block for stereoselective synthesis of complex organic molecules. Utilised in reactions requiring precise control over stereochemistry.
Pharmaceutical Intermediates
Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Enables the construction of chiral centres essential for drug efficacy.
Organic Synthesis
A versatile reagent for various organic transformations, including cyclisation and functionalisation reactions. Useful for creating lactone-containing scaffolds.
Chiral Pool Synthesis
Component of the chiral pool, providing a readily available source of chirality for synthetic strategies. Facilitates the development of enantiomerically pure compounds.
| Molecular weight | 158.15 |
|---|---|
| Empirical formula | C7H10O4 |
| Assay | 95% |
| Boiling point | 151-155 °C/12 mmHg(lit.) |
| Density | 1.163 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.448(lit.) |
| Optical activity | [α]20/D −12°, c = 0.4 in ethanol |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone used for?
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(R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of pharmaceuticals and fine chemicals.
What is the CAS number and formula for (R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone?
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The CAS number is 33019-03-3 and the empirical formula is C7H10O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This compound is combustible and requires appropriate personal protective equipment, including eyeshields and gloves. Ventilation is necessary, and a respirator may be required for certain applications. Consult the Safety Data Sheet for detailed information.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling shipments and exports worldwide.
How can I request a sample or quote for (R)-(−)-γ-Ethoxycarbonyl-γ-butyrolactone?
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Please contact our sales team via the website or direct email to request a sample or a quotation for this product.
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