(R)-1,1-Diphenyl-1-fluoro-2-aminopropane
(R)-1,1-Diphenyl-1-fluoro-2-aminopropane (CAS 352534-91-9) is a chiral fluorinated building block with a molecular weight of 229.29 g/mol. This amine derivative is valuable in asymmetric synthesis, offering a unique fluorinated structure for creating complex molecules. It serves as a key intermediate in organic synthesis, particularly for researchers developing novel pharmaceuticals and advanced materials where precise stereochemistry and fluorine incorporation are critical.
- Synonyms
- F(C6H5)2CCH(NH2)CH3
Chiral Synthesis
Utilised as a chiral building block in asymmetric synthesis to introduce stereochemical complexity in target molecules. Its fluorinated diphenylmethyl group offers unique steric and electronic properties.
Pharmaceutical Intermediates
Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) where fluorination and specific chirality are required for biological activity. Enables the development of novel drug candidates.
Organic Fluorine Chemistry
Incorporates a fluorine atom into organic structures, a common strategy to modify properties such as metabolic stability, lipophilicity, and binding affinity in bioactive compounds.
Materials Science
Potential applications in the development of specialised organic materials, leveraging the unique properties imparted by the fluorinated and chiral centres.
| Molecular weight | 229.29 |
|---|---|
| Linear formula | F(C6H5)2CCH(NH2)CH3 |
| Assay | 97% |
| Optical activity | [α]20/D +30°, c = 1% in chloroform |
| Melting point | 47-51 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1,1-Diphenyl-1-fluoro-2-aminopropane used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and advanced organic materials, especially where fluorination and specific stereochemistry are important.
What is the CAS number and formula for (R)-1,1-Diphenyl-1-fluoro-2-aminopropane?
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The CAS number is 352534-91-9. The linear formula is F(C6H5)2CCH(NH2)CH3, and its molecular weight is 229.29 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. It is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
How is (R)-1,1-Diphenyl-1-fluoro-2-aminopropane packed, shipped, and exported?
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Tech Serve Solutions offers professional packing and shipping services for chemicals, adhering to international regulations for safe transport. We export globally to qualified research and industrial clients.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by email, providing your specific requirements and shipping details.
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