(R)-1,4-Benzodioxane-2-carboxylic acid
(R)-1,4-Benzodioxane-2-carboxylic acid (CAS 70918-53-5) is a chiral building block with the molecular formula C9H8O4 and a molecular weight of 180.16. This compound is a key intermediate in asymmetric synthesis, offering a valuable scaffold for the construction of complex chiral molecules. Its specific stereochemistry makes it particularly useful in the development of pharmaceuticals and other fine chemicals where enantiomeric purity is critical.
- IUPAC
- (R)-2,3-Dihydro-1,4-benzodioxin-2-carboxylic acid
- Synonyms
- (R)-2,3-Dihydro-1,4-benzodioxin-2-carboxylic acid1,4-Benzodioxan-2-carboxylic acid, (R)-
Chiral Intermediate in Organic Synthesis
Serves as a crucial enantiomerically pure building block for synthesizing complex chiral molecules, particularly in pharmaceutical research and development.
Asymmetric Synthesis
Utilised in asymmetric synthesis strategies to introduce chirality into target molecules, ensuring specific stereochemical outcomes in chemical reactions.
Development of Pharmaceutical Agents
A valuable precursor in the synthesis of biologically active compounds, where precise stereochemistry is often linked to efficacy and safety.
Research and Development
Employed in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities.
| Molecular weight | 180.16 |
|---|---|
| Empirical formula | C9H8O4 |
| Assay | ≥97.0% (sum of enantiomers, GC) |
| Optical activity | [α]20/D +83±2°, c = 1.5% in chloroform |
| Optical purity | enantiomeric ratio: ≥99.0:1.0 |
| Melting point | 96-99 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1,4-Benzodioxane-2-carboxylic acid used for?
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(R)-1,4-Benzodioxane-2-carboxylic acid is primarily used as a chiral building block in asymmetric synthesis and for the development of pharmaceutical agents and other fine chemicals where specific stereochemistry is important.
What are the CAS number and formula for (R)-1,4-Benzodioxane-2-carboxylic acid?
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The CAS number is 70918-53-5, and its empirical formula is C9H8O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97.0% (sum of enantiomers, GC) and an enantiomeric ratio of ≥99.0:1.0. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How is (R)-1,4-Benzodioxane-2-carboxylic acid handled and what are the safety considerations?
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This compound is classified with GHS07 symbol and a Warning signal word, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended PPE includes a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust.
How are your chemicals packed, shipped, and exported?
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We carefully pack our chemicals according to international shipping regulations and export them globally, ensuring product integrity and compliance.
How can I request a sample or a quote for (R)-1,4-Benzodioxane-2-carboxylic acid?
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Please contact our sales department through our website or by phone to request a sample or a quotation for this product.
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