(R)-1,1,1-Trifluoro-2-propanol
(R)-1,1,1-Trifluoro-2-propanol (CAS: 17628-73-8; C3H5F3O) is a chiral fluorinated alcohol with a molecular weight of 114.07 g/mol. This compound is recognised for its utility as a building block in organic synthesis and chemical research. Its unique trifluoromethyl group and chiral centre make it a valuable intermediate for creating complex molecules. Available at 97% purity, it is stored under refrigeration at 2-8°C to maintain its integrity.
- IUPAC
- (R)-1,1,1-Trifluoropropan-2-ol
- Synonyms
- 17628-73-8, C3H5F3O, (R)-1,1,1-Trifluoropropan-2-ol

Chiral Building Block
Utilised in asymmetric synthesis for the construction of enantiomerically pure compounds. Its trifluoromethyl group can impart desirable properties to target molecules.
Organic Synthesis Intermediate
Serves as a versatile intermediate in the creation of diverse organic structures. Its reactivity is characteristic of secondary alcohols, modified by the electron-withdrawing trifluoromethyl group.
Research and Development
Employed in academic and industrial R&D settings for the exploration of new chemical pathways and the synthesis of novel compounds.
| Molecular weight | 114.07 |
|---|---|
| Empirical formula | C3H5F3O |
| Assay | 97% |
| Optical activity | [α]22/D +8.3°, c = 1% in chloroform |
| Storage temperature | 2-8°C |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 18 °C / 64.4 °F |
|---|---|
| Transport (UN / ADR) | UN 1987BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1,1,1-Trifluoro-2-propanol used for?
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(R)-1,1,1-Trifluoro-2-propanol is primarily used as a chiral building block in organic synthesis and for chemical research and development purposes.
What is the CAS number and formula for (R)-1,1,1-Trifluoro-2-propanol?
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The CAS number is 17628-73-8, and its empirical formula is C3H5F3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1,1,1-Trifluoro-2-propanol with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should (R)-1,1,1-Trifluoro-2-propanol be handled and stored?
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This compound is flammable with a flash point of 18°C and is an irritant to skin, eyes, and respiratory tract. It requires handling with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store refrigerated at 2-8°C.
Is (R)-1,1,1-Trifluoro-2-propanol a controlled substance?
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The provided data does not indicate that (R)-1,1,1-Trifluoro-2-propanol is a controlled substance.
How is this chemical packed and shipped?
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This product is shipped as a dangerous good, UN 1987, Class 3, Packing Group II. Specific packaging details can be provided upon request.
How can I request a sample or quote for (R)-1,1,1-Trifluoro-2-propanol?
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To request a sample or quote, please contact our sales team through our website or by phone, providing the product name and CAS number.
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