(R)-(−)-γ-Trityloxymethyl-γ-butyrolactone
(R)-(−)-γ-Trityloxymethyl-γ-butyrolactone (CAS 78158-90-4, C24H22O3) is a chiral building block with a molecular weight of 358.43 g/mol. This compound serves as a valuable intermediate in asymmetric synthesis and organic chemistry. It has been notably employed in the synthesis of target pentonolactones, facilitating studies on the interaction of γ-lactones with the phorbol ester receptor of protein kinase. Supplied by TSS, it is available with a minimum assay of 98%.
- IUPAC
- (R)-(−)-Dihydro-5-trityloxymethyl-2(3H)-furanone,5-O-Trityl-2,3-dideoxy-L-glyceropentono-1,4-lactone
- Synonyms
- (R)-(−)-Dihydro-5-trityloxymethyl-2(3H)-furanone5-O-Trityl-2,3-dideoxy-L-glyceropentono-1,4-lactone
Synthesis of Pentonolactones
This lactone derivative has been utilized in the synthetic pathways leading to pentonolactones. These target molecules are crucial for investigating the biological interactions of gamma-lactones with specific protein receptors, such as the phorbol ester receptor of protein kinase.
Chiral Building Block in Organic Synthesis
As a chiral molecule, (R)-(−)-γ-Trityloxymethyl-γ-butyrolactone is an important building block for the stereoselective construction of complex organic molecules. Its defined stereochemistry allows for precise control in asymmetric synthesis applications.
Research in Chemical Biology
The compound facilitates research into the mechanisms of action for biologically relevant molecules like lactones. Its use in interaction studies provides insights into the molecular basis of cellular signalling pathways.
| Molecular weight | 358.43 |
|---|---|
| Empirical formula | C24H22O3 |
| Assay | 98% |
| Optical activity | [α]20/D −26°, c = 1 in methylene chloride |
| Application | This compound was used in the synthesis of target pentonolactones for interaction studies of γ-lactones with the phorbol ester receptor of protein kinase1 |
| Melting point | 150-152 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-γ-Trityloxymethyl-γ-butyrolactone used for?
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This compound is primarily used as a chiral building block in organic synthesis, particularly in the preparation of target pentonolactones for interaction studies with biological receptors like the phorbol ester receptor of protein kinase.
What is the CAS number and chemical formula for this product?
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The CAS number is 78158-90-4 and the chemical formula is C24H22O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-γ-Trityloxymethyl-γ-butyrolactone with a minimum assay of 98%. This product is not intended for USP, BP, EP, or any pharmacopoeia, nutraceutical, food, or medicinal use. It is supplied for research and chemical synthesis purposes only.
How should (R)-(−)-γ-Trityloxymethyl-γ-butyrolactone be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter, such as type N95 (US) or P1 (EN143), should be used if airborne exposure is possible. This compound is classified with a WGK rating of 3 in Germany, indicating a significant hazard to water.
Is this compound subject to any special shipping or export controls?
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The provided data does not indicate any specific controlled substance status or special shipping regulations beyond standard chemical handling requirements. Tech Serve Solutions exports globally, adhering to all applicable international shipping regulations for chemical products.
How can I request a sample or a quote for this chemical?
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To request a sample or obtain a quotation, please use the contact form on the Tech Serve Solutions website or contact our sales department directly, referencing the product name and CAS number 78158-90-4.
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