(R)-1-Boc-2-methylpyrrolidine
(R)-1-Boc-2-methylpyrrolidine (CAS: 157007-54-0, C10H19NO2) is a chiral heterocyclic compound with a molecular weight of 185.26 g/mol. This tert-butyl carbamate derivative serves as a valuable building block in asymmetric synthesis. Its defined stereochemistry makes it crucial for constructing complex chiral molecules, particularly in the pharmaceutical and fine chemical industries. Tech Serve Solutions supplies this reagent with high purity for demanding synthetic applications.
- IUPAC
- tert-Butyl (R)-2-methylpyrrolidine-1-carboxylate
- Synonyms
- tert-Butyl (R)-2-methylpyrrolidine-1-carboxylate

Chiral Building Block in Asymmetric Synthesis
Utilised as a stereodefined precursor for the synthesis of chiral amines and other complex organic molecules. Its pyrrolidine core with a defined (R) stereocenter is essential for introducing specific chirality.
Pharmaceutical Intermediate Synthesis
Serves as a key intermediate in the development of active pharmaceutical ingredients (APIs) where specific stereoisomers are required for therapeutic efficacy and safety.
Research and Development
Employed in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities.
| Molecular weight | 185.26 |
|---|---|
| Empirical formula | C10H19NO2 |
| Assay | 97% |
| Density | 0.960 g/mL at 25 °C |
| Refractive index | n20/D 1.447 |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-2-methylpyrrolidine used for?
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(R)-1-Boc-2-methylpyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and fine chemicals.
What is the CAS number and formula for (R)-1-Boc-2-methylpyrrolidine?
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The CAS number is 157007-54-0 and the empirical formula (Hill notation) is C10H19NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-Boc-2-methylpyrrolidine with an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-1-Boc-2-methylpyrrolidine be handled safely?
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This compound is a Warning (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation and use appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C.
Is (R)-1-Boc-2-methylpyrrolidine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (R)-1-Boc-2-methylpyrrolidine.
How can I request a quote or sample of (R)-1-Boc-2-methylpyrrolidine?
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Please contact our sales team or use the online inquiry form on our website to request a quote or sample of (R)-1-Boc-2-methylpyrrolidine.
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