(R)-1-Boc-3-cyanopyrrolidine
(R)-1-Boc-3-cyanopyrrolidine (CAS: 132945-76-7), with the molecular formula C10H16N2O2 and a molecular weight of 196.25, is a valuable chiral building block. It plays a significant role in asymmetric synthesis and general chemical synthesis. Its heterocyclic pyrrolidine structure, functionalised with a Boc protecting group and a nitrile, makes it a versatile intermediate for creating complex organic molecules, particularly within pharmaceutical research and development.
Asymmetric Synthesis
This chiral pyrrolidine derivative is employed in stereoselective reactions to build complex molecules with defined stereochemistry. It serves as a key intermediate in the synthesis of enantiomerically pure compounds.
Pharmaceutical Intermediates
It functions as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its structure is found in various drug candidates and marketed pharmaceuticals.
Heterocyclic Chemistry
As a functionalised pyrrolidine, it is used in the construction of diverse heterocyclic frameworks. These motifs are prevalent in medicinal chemistry and materials science.
Chemical Research
Researchers utilise this compound in exploring novel synthetic pathways and developing new chemical entities. Its availability supports advancements in organic synthesis methodologies.
| Molecular weight | 196.25 |
|---|---|
| Empirical formula | C10H16N2O2 |
| Assay | ≥95.5% (HPLC)96% |
| Optical activity | [α]/D -21.0±2.0°, c = 1 in methanol |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-3-cyanopyrrolidine used for?
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It is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of pharmaceuticals and other complex organic molecules.
What is the CAS number and formula for (R)-1-Boc-3-cyanopyrrolidine?
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The CAS number is 132945-76-7, and its molecular formula is C10H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-Boc-3-cyanopyrrolidine with a purity of ≥95.5% (HPLC) or 96%. This product is typically supplied for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should (R)-1-Boc-3-cyanopyrrolidine be handled?
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Handling requires caution. It is classified with GHS07 and a 'Warning' signal word. Specific hazards include skin irritation (H315), serious eye irritation (H319), and respiratory tract irritation (H335). Always use appropriate personal protective equipment, ensure good ventilation, and avoid breathing dust/fume/gas/mist/vapours/spray (P261). In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is (R)-1-Boc-3-cyanopyrrolidine a controlled substance?
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The provided data does not indicate that (R)-1-Boc-3-cyanopyrrolidine is a controlled substance.
How is (R)-1-Boc-3-cyanopyrrolidine packed and shipped?
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(R)-1-Boc-3-cyanopyrrolidine is carefully packed and exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations for chemical compounds.
How can I request a quote or sample?
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To request a quote or sample of (R)-1-Boc-3-cyanopyrrolidine, please use the contact form on our website or contact our sales team directly.
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